Product: FOXI1 Antibody
Catalog: DF8818
Description: Rabbit polyclonal antibody to FOXI1
Application: WB
Reactivity: Human, Mouse
Prediction: Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 40 kDa; 41kD(Calculated).
Uniprot: Q12951
RRID: AB_2842015

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(100%), Horse(100%), Sheep(100%), Rabbit(80%), Dog(80%)
Clonality:
Polyclonal
Specificity:
FOXI1 Antibody detects endogenous levels of total FOXI1.
RRID:
AB_2842015
Cite Format: Affinity Biosciences Cat# DF8818, RRID:AB_2842015.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FKH10; FKHL10; Forkhead (Drosophila) like 10; Forkhead box I1; Forkhead box protein I1; Forkhead like 10; Forkhead related activator 6; Forkhead related transcription factor 6; Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FOXI1; FOXI1_HUMAN; FREAC 6; FREAC-6; FREAC6; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH 3; HFH-3; HFH3; HNF 3/fork head homolog 3; HNF-3 fork-head homolog 3; HNF-3/fork-head homolog 3; Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds; MGC34197;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q12951 FOXI1_HUMAN:

Expressed in kidney.

Sequence:
MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLYPREGTEV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
80
Rabbit
80
Pig
70
Xenopus
60
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q12951 As Substrate

Site PTM Type Enzyme
S10 Phosphorylation
Y126 Phosphorylation
S127 Phosphorylation
S170 Phosphorylation
S176 Phosphorylation
S220 Phosphorylation
S237 Phosphorylation
S242 Phosphorylation
S256 Phosphorylation

Research Backgrounds

Function:

Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity).

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in kidney.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.