Product: PLXDC2 Antibody
Catalog: DF8840
Description: Rabbit polyclonal antibody to PLXDC2
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 60~80 kDa; 60kD(Calculated).
Uniprot: Q6UX71
RRID: AB_2842037

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
PLXDC2 Antibody detects endogenous levels of total PLXDC2.
RRID:
AB_2842037
Cite Format: Affinity Biosciences Cat# DF8840, RRID:AB_2842037.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ14623; Plexin domain containing 2; Plexin domain containing protein 2; Plexin domain-containing protein 2; PLXDC 2; plxdc2; PXDC2_HUMAN; TEM7R; Tumor endothelial marker 7 related protein; Tumor endothelial marker 7-related protein;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q6UX71 PXDC2_HUMAN:

Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue.

Sequence:
MARFPKADLAAAGVMLLCHFFTDQFQFADGKPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPRSFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPSDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKMCENTEPVETSSRTTTTVGATTTQFRVLTTTRRAVTSQFPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIIGILILVLIVATAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6UX71 As Substrate

Site PTM Type Enzyme
S86 O-Glycosylation
S86 Phosphorylation
N103 N-Glycosylation
S150 Phosphorylation
T152 Phosphorylation
N160 N-Glycosylation
T395 Phosphorylation
T400 Phosphorylation
T414 Phosphorylation
S415 Phosphorylation
T419 Phosphorylation
S495 Phosphorylation
K501 Ubiquitination
S506 Phosphorylation
Y511 Phosphorylation

Research Backgrounds

Function:

May play a role in tumor angiogenesis.

Subcellular Location:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue.

Subunit Structure:

Interacts with CTTN.

Family&Domains:

Belongs to the plexin family.

Restrictive clause

 

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For Research Use Only.
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