LMTK1 Antibody - #DF8841

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Product: LMTK1 Antibody
Catalog: DF8841
Description: Rabbit polyclonal antibody to LMTK1
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Sheep
Mol.Wt.: 145 kDa; 145kD(Calculated).
Uniprot: Q6ZMQ8
RRID: AB_2842038

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Sheep(100%)
Clonality:
Polyclonal
Specificity:
LMTK1 Antibody detects endogenous levels of total LMTK1.
RRID:
AB_2842038
Cite Format: Affinity Biosciences Cat# DF8841, RRID:AB_2842038.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AATK; AATYK; AATYK1; Apoptosis associated tyrosine kinase; Apoptosis-associated tyrosine kinase; Brain apoptosis associated tyrosine kinase; Brain apoptosis-associated tyrosine kinase; CDK5 binding protein; CDK5-binding protein; KIAA0641; Lemur tyrosine kinase 1; LMR1; LMTK1; LMTK1_HUMAN; p35 binding protein; p35-binding protein; p35BP; Serine/threonine protein kinase LMTK1; Serine/threonine-protein kinase LMTK1;

Immunogens

Immunogen:
Uniprot:

Q6ZMQ8(LMTK1_HUMAN) >>Visit HPA database.

Gene(ID):
AATK(9625)
Expression:
Q6ZMQ8 LMTK1_HUMAN:

Expressed in brain.

Sequence:
MSSSFFNPSFAFSSHFDPDGAPLSELSWPSSLAVVAVSFSGLFAVIVLMLACLCCKKGGIGFKEFENAEGDEYAADLAQGSPATAAQNGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDVGRHSLLYLKEIGRGWFGKVFLGEVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGATEAEEEFERRWRSLRPGGGGVGPGPGAAGPMLGGVVELAAASSFPLLEQFAGDGFHADGDDVLTVTETSRGLNFEYKWEAGRGAEAFPATLSPGRTARLQELCAPDGAPPGVVPVLSAHSPSLGSEYFIRLEEAAPAAGHDPDCAGCAPSPPATADQDDDSDGSTAASLAMEPLLGHGPPVDVPWGRGDHYPRRSLARDPLCPSRSPSPSAGPLSLAEGGAEDADWGVAAFCPAFFEDPLGTSPLGSSGAPPLPLTGEDELEEVGARRAAQRGHWRSNVSANNNSGSRCPESWDPVSAGGHAEGCPSPKQTPRASPEPGYPGEPLLGLQAASAQEPGCCPGLPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQEGAPLPSEEASAPDAPDALPDSPTPATGGEVSAIKLASALNGSSSSPEVEAPSSEDEDTAEATSGIFTDTSSDGLQARRPDVVPAFRSLQKQVGTPDSLDSLDIPSSASDGGYEVFSPSATGPSGGQPRALDSGYDTENYESPEFVLKEAQEGCEPQAFAELASEGEGPGPETRLSTSLSGLNEKNPYRDSAYFSDLEAEAEATSGPEKKCGGDRAPGPELGLPSTGQPSEQVCLRPGVSGEAQGSGPGEVLPPLLQLEGSSPEPSTCPSGLVPEPPEPQGPAKVRPGPSPSCSQFFLLTPVPLRSEGNSSEFQGPPGLLSGPAPQKRMGGPGTPRAPLRLALPGLPAALEGRPEEEEEDSEDSDESDEELRCYSVQEPSEDSEEEAPAVPVVVAESQSARNLRSLLKMPSLLSETFCEDLERKKKAVSFFDDVTVYLFDQESPTRELGEPFPGAKESPPTFLRGSPGSPSAPNRPQQADGSPNGSTAEEGGGFAWDDDFPLMTAKAAFAMALDPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKRGPEAGAGGESKEA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Chicken
57
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6ZMQ8 As Substrate

Site PTM Type Enzyme
K57 Acetylation
Y73 Phosphorylation P06241 (FYN)
S81 Phosphorylation
Y93 Phosphorylation P06241 (FYN)
S222 Phosphorylation
Y283 Phosphorylation
T286 Phosphorylation
Y479 Phosphorylation
S495 Phosphorylation
S700 Phosphorylation
T941 Phosphorylation
S946 Phosphorylation
S968 Phosphorylation
S999 Phosphorylation
S1215 Phosphorylation
K1260 Acetylation
S1262 Phosphorylation
S1340 Phosphorylation
T1344 Phosphorylation
S1345 Phosphorylation

Research Backgrounds

Function:

May be involved in neuronal differentiation.

PTMs:

Autophosphorylated. Phosphorylated by CDK5.

Subcellular Location:

Membrane>Single-pass type I membrane protein. Cytoplasm. Cytoplasm>Perinuclear region.
Note: Predominantly perinuclear.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain.

Subunit Structure:

Interacts with CDK5.

Family&Domains:

Belongs to the protein kinase superfamily. Tyr protein kinase family.

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