TSH1 Antibody - #DF8843

(2)  
Product: TSH1 Antibody
Catalog: DF8843
Description: Rabbit polyclonal antibody to TSH1
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 117 kDa; 118kD(Calculated).
Uniprot: Q6ZSZ6
RRID: AB_2842040

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(90%), Horse(92%), Rabbit(92%), Dog(92%), Chicken(92%), Xenopus(83%)
Clonality:
Polyclonal
Specificity:
TSH1 Antibody detects endogenous levels of total TSH1.
RRID:
AB_2842040
Cite Format: Affinity Biosciences Cat# DF8843, RRID:AB_2842040.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Antigen NY CO 33; NY CO 33; NYCO33; SDCCAG33; Serologically defined colon cancer antigen 33; Teashirt family zinc finger 1; Teashirt homolog 1; Teashirt zinc finger 1; Teashirt zinc finger homeobox 1; TSH1;

Immunogens

Immunogen:
Uniprot:

Q6ZSZ6(TSH1_HUMAN) >>Visit HPA database.

Gene(ID):
TSHZ1(10194)
Expression:
Q6ZSZ6 TSH1_HUMAN:

Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.

Sequence:
MPRRKQQAPRRSAAYVPEEELKAAEIDEEHVEDDGLSLDIQESEYMCNEETEIKEAQSYQNSPVSSATNQDAGYGSPFSESSDQLAHFKGSSSREEKEDPQCPDSVSYPQDSLAQIKAVYANLFSESCWSSLALDLKKSGSTTSTNDASQKESSAPTPTPPTCPVSTTGPTTSTPSTSCSSSTSHSSTTSTSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLAPPCSPEPAGMAAEVALSESAKDQKAANPYVTPNNRYGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPASSIKKQPDSPAGSTTSEEKKEPEKEKPPVAGDAEKIKEESEDSLEKFEPSTLYPYLREEDLDDSPKGGLDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPLPAAVQSVQVQPSYAGGVKSLSSAEHNALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVNIKKEERPPEKEKSSLAKAASPIAKENKDFPKTEEVSGKPQKKGPEAETGKAKKEGPLDVHTPNGTEPLKAKVTNGCNNLGIIMDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLAMLYKISNSMLDKPVYPATPVKQADAIDRYYYENSDQPIDLTKSKNKPLVSSVADSVASPLRESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNWNPQHLLILQAQFASSLRETTEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFSLKDLSKLPLNQIQEQQNVSKVLTNKTLGPLGATEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYVTELEKQ

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
92
Dog
92
Chicken
92
Rabbit
92
Bovine
90
Xenopus
83
Zebrafish
78
Sheep
67
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6ZSZ6 As Substrate

Site PTM Type Enzyme
S62 Phosphorylation
S76 Phosphorylation
K89 Ubiquitination
K278 Acetylation
S293 Phosphorylation
Y332 Phosphorylation
K334 Ubiquitination
S364 Phosphorylation
S379 Phosphorylation
S447 Phosphorylation
S482 Phosphorylation
S489 Phosphorylation
S523 Phosphorylation
Y533 Phosphorylation
S623 Phosphorylation
S626 Phosphorylation
S671 Phosphorylation
T712 Phosphorylation
S765 Phosphorylation
K814 Ubiquitination
S822 Phosphorylation
S830 Phosphorylation
S835 Phosphorylation
S841 Phosphorylation
T852 Phosphorylation
K854 Ubiquitination
S941 Phosphorylation
K1016 Ubiquitination
S1035 Phosphorylation

Research Backgrounds

Function:

Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.

Subunit Structure:

Interacts (via homeobox domain) with APBB1 (via PID domain 1).

Family&Domains:

Belongs to the teashirt C2H2-type zinc-finger protein family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.