Histone H1X Antibody - #DF8855
| Product: | Histone H1X Antibody |
| Catalog: | DF8855 |
| Description: | Rabbit polyclonal antibody to Histone H1X |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Sheep, Xenopus |
| Mol.Wt.: | 22kDa; 22kD(Calculated). |
| Uniprot: | Q92522 |
| RRID: | AB_2842052 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8855, RRID:AB_2842052.
Fold/Unfold
H1 histone family member X; H1FX; H1X; H1X_HUMAN; Histone H1x; MGC15959; MGC8350;
Immunogens
- Q92522 H1X_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNRKKLEGGGERRGAPAAATAPAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQRSHKKGAGAKKDKGGKAKKTAAAGGKKVKKAAKPSVPKVPKGRK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92522 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| T22 | Phosphorylation | Uniprot | |
| K23 | Ubiquitination | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| S33 | Phosphorylation | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| K47 | Acetylation | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| R57 | Methylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| R128 | Methylation | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K146 | Methylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K174 | Acetylation | Uniprot | |
| K179 | Acetylation | Uniprot | |
| K180 | Acetylation | Uniprot | |
| K182 | Acetylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| K195 | Acetylation | Uniprot | |
| K196 | Acetylation | Uniprot | |
| K196 | Methylation | Uniprot | |
| K198 | Acetylation | Uniprot | |
| K199 | Acetylation | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| K207 | Methylation | Uniprot | |
| K210 | Methylation | Uniprot |
Research Backgrounds
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Citrullination at Arg-62 (H1R54ci) by PADI4 takes place within the DNA-binding site of H1 and results in its displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance.
Nucleus. Chromosome.
Expressed ubiquitously.
Interacts with RRP1B.
Belongs to the histone H1/H5 family.
Restrictive clause
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For Research Use Only.
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