ARHGEF17 Antibody - #DF8862

(2)  
Product: ARHGEF17 Antibody
Catalog: DF8862
Description: Rabbit polyclonal antibody to ARHGEF17
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Sheep, Rabbit, Dog
Mol.Wt.: 221 kDa; 222kD(Calculated).
Uniprot: Q96PE2
RRID: AB_2842059

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(91%), Bovine(100%), Sheep(100%), Rabbit(91%), Dog(82%)
Clonality:
Polyclonal
Specificity:
ARHGEF17 Antibody detects endogenous levels of total ARHGEF17.
RRID:
AB_2842059
Cite Format: Affinity Biosciences Cat# DF8862, RRID:AB_2842059.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

164 kDa Rho specific guanine nucleotide exchange factor; ARHGEF 17; ARHGEF17; FLJ90019; KIAA0337; p164 RhoGEF; P164RHOGEF; Rho guanine nucleotide exchange factor (GEF) 17; Rho guanine nucleotide exchange factor 17; Rho specific guanine nucleotide exchange factor 164 kDa; TEM 4; Tumor endothelial marker 4;

Immunogens

Immunogen:
Uniprot:

Q96PE2(ARHGH_HUMAN) >>Visit HPA database.

Gene(ID):
ARHGEF17(9828)
Expression:
Q96PE2 ARHGH_HUMAN:

Highly expressed in the heart.

Sequence:
MADGAPRPQLYRSVSFKLLERWSGGPGLREEDTDTPGLRRRASCRPTTAARGQPSRRVSKLASGPLAAPAQPRPLRSLSPSVRQLSRRFDAPRLDDGSAGTRDGGVLPAAAEEAAEGPARGAWPSVTEMRKLFGGPGSRRPSADSESPGTPSPDGAAWEPPARESRQPPTPPPRTCFPLAGLRSARPLTGPETEGRLRRPQQQQERAQRPADGLHSWHIFSQPQAGARASCSSSSIAASYPVSRSRAASSSEEEEEGPPQLPGAQSPAYHGGHSSGSDDDRDGEGGHRWGGRPGLRPGSSLLDQDCRPDSDGLNLSSMNSAGVSGSPEPPTSPRAPREEGLREWGSGSPPCVPGPQEGLRPMSDSVGGAFRVAKVSFPSYLASPAGSRGSSRYSSTETLKDDDLWSSRGSGGWGVYRSPSFGAGEGLLRSQARTRAKGPGGTSRALRDGGFEPEKSRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLKDLTATLRRAKSFTCSEKPMARRLPRTSALKSSSSELLLTGPGAEEDPLPLIVQDQYVQEARQVFEKIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQEELSGPESSLTDEGIGADPEPPVAAFCGLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWALVSPETPPTPGALRRRRKVPPSGSGGSELSNGEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHSDWSVGSEESKGYQEVIQSIVQGPGTLGRVVDDRIAGKAPKKKSLSDPSRRGELAGPGFEGPGGEPIREVEPMLPPSSSEPILVEQRAEPEEPGATRSRAQSERALPEALPPPATAHRNFHLDPKLADILSPRLIRRGSKKRPARSSHQELRRDEGSQDQTGSLSRARPSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVPAPVPVDMPCLPLAAPPSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Pig
91
Rabbit
91
Dog
82
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96PE2 As Substrate

Site PTM Type Enzyme
S15 Phosphorylation
T33 Phosphorylation
T35 Phosphorylation
S43 Phosphorylation
R45 Methylation
S63 Phosphorylation
S79 Phosphorylation
S138 Phosphorylation
S142 Phosphorylation
T150 Phosphorylation
S152 Phosphorylation
T170 Phosphorylation
T189 Phosphorylation
S230 Phosphorylation
S232 Phosphorylation
S233 Phosphorylation
S332 Phosphorylation
S346 Phosphorylation
S376 Phosphorylation
S379 Phosphorylation
Y380 Phosphorylation
S383 Phosphorylation
S387 Phosphorylation
S390 Phosphorylation
S391 Phosphorylation
Y393 Phosphorylation
S394 Phosphorylation
S395 Phosphorylation
T396 Phosphorylation
S410 Phosphorylation
S418 Phosphorylation
S420 Phosphorylation
R429 Methylation
R433 Methylation
S461 Phosphorylation
S463 Phosphorylation
S476 Phosphorylation
S507 Phosphorylation
S509 Phosphorylation
S527 Phosphorylation
T530 Phosphorylation
K535 Acetylation
S546 Phosphorylation
S566 Phosphorylation
S567 Phosphorylation
S568 Phosphorylation
S569 Phosphorylation
T574 Phosphorylation
K601 Ubiquitination
S613 Phosphorylation
S619 Phosphorylation
T702 Phosphorylation P28482 (MAPK1)
S733 Phosphorylation
S735 Phosphorylation
T751 Phosphorylation
S762 Phosphorylation
S764 Phosphorylation
S787 Phosphorylation
S790 Phosphorylation
T809 Phosphorylation
S827 Phosphorylation
S829 Phosphorylation
S885 Phosphorylation
T898 Phosphorylation
S914 Phosphorylation
S930 Phosphorylation
S940 Phosphorylation
T944 Phosphorylation
S946 Phosphorylation
S948 Phosphorylation
S961 Phosphorylation
S1002 Phosphorylation
T1007 Phosphorylation
S1192 Phosphorylation
K1245 Ubiquitination
S1331 Phosphorylation
T1336 Phosphorylation
S1345 Phosphorylation
T1385 Phosphorylation
S1430 Phosphorylation
K1470 Ubiquitination
S1478 Phosphorylation
S1513 Phosphorylation
S1521 Phosphorylation
S1663 Phosphorylation
T1669 Phosphorylation
S1717 Phosphorylation
S1720 Phosphorylation
S1725 Phosphorylation
S1811 Phosphorylation
S1961 Phosphorylation
T1991 Phosphorylation
S2005 Phosphorylation
S2011 Phosphorylation

Research Backgrounds

Function:

Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.

Tissue Specificity:

Highly expressed in the heart.

Restrictive clause

 

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