SRRM2 Antibody - #DF8889

(1)  
Product: SRRM2 Antibody
Catalog: DF8889
Description: Rabbit polyclonal antibody to SRRM2
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 300kDa; 300kD(Calculated).
Uniprot: Q9UQ35
RRID: AB_2842085

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(91%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
SRRM2 Antibody detects endogenous levels of total SRRM2.
RRID:
AB_2842085
Cite Format: Affinity Biosciences Cat# DF8889, RRID:AB_2842085.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

300 kDa nuclear matrix antigen; CWC21; KIAA0324; Ser/Arg-related nuclear matrix protein of 300 kDa; Serine/arginine repetitive matrix protein 2; Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa; Splicing coactivator subunit SRm300; SR-related nuclear matrix protein of 300 kDa; SRL300; SRM300; SRRM2; SRRM2_HUMAN; Tax-responsive enhancer element-binding protein 803; TaxREB803;

Immunogens

Immunogen:
Uniprot:

Q9UQ35(SRRM2_HUMAN) >>Visit HPA database.

Gene(ID):
SRRM2(23524)
Expression:
Q9UQ35 SRRM2_HUMAN:

Expressed in liver, placenta, and white blood cells.

Sequence:
MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Sheep
100
Dog
100
Rabbit
100
Pig
91
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UQ35 As Substrate

Site PTM Type Enzyme
M1 Acetylation
Y2 Phosphorylation
T9 Phosphorylation
R11 Methylation
S13 Phosphorylation
Y18 Phosphorylation
R21 Methylation
S24 Phosphorylation
R27 Methylation
R30 Methylation
R33 Methylation
Y36 Phosphorylation
K37 Acetylation
K37 Ubiquitination
K51 Ubiquitination
Y82 Phosphorylation
K90 Methylation
K101 Ubiquitination
K108 Ubiquitination
T111 Phosphorylation
T121 Phosphorylation
K130 Ubiquitination
S142 Phosphorylation
S144 Phosphorylation
Y145 Phosphorylation
S150 Phosphorylation
K169 Acetylation
K169 Ubiquitination
S177 Phosphorylation
S178 Phosphorylation
S179 Phosphorylation
S180 Phosphorylation
S182 Phosphorylation
T184 Phosphorylation
S200 Phosphorylation
S202 Phosphorylation
S203 Phosphorylation
S204 Phosphorylation
S212 Phosphorylation
S220 Phosphorylation
S222 Phosphorylation
S224 Phosphorylation
S231 Phosphorylation
T233 Phosphorylation
S236 Phosphorylation
S248 Phosphorylation
S250 Phosphorylation
T251 Phosphorylation
T252 Phosphorylation
S257 Phosphorylation
S263 Phosphorylation
T264 Phosphorylation
S265 Phosphorylation
S268 Phosphorylation
S270 Phosphorylation
S272 Phosphorylation
T274 Phosphorylation
S275 Phosphorylation
S277 Phosphorylation
K285 Ubiquitination
T286 Phosphorylation
T288 Phosphorylation
T289 Phosphorylation
S295 Phosphorylation
S297 Phosphorylation
S300 Phosphorylation
S311 Phosphorylation
T315 Phosphorylation
T316 Phosphorylation
S317 Phosphorylation
T318 Phosphorylation
S322 Phosphorylation
S323 Phosphorylation
T326 Phosphorylation
T328 Phosphorylation
S332 Phosphorylation
S333 Phosphorylation
Y335 Phosphorylation
S346 Phosphorylation
T348 Phosphorylation
S351 Phosphorylation
S353 Phosphorylation
S357 Phosphorylation
S358 Phosphorylation
T359 Phosphorylation
T367 Phosphorylation
S377 Phosphorylation
T383 Phosphorylation
T384 Phosphorylation
S387 Phosphorylation
S395 Phosphorylation
S398 Phosphorylation
T400 Phosphorylation
S404 Phosphorylation
S408 Phosphorylation
S415 Phosphorylation
S416 Phosphorylation
S417 Phosphorylation
S418 Phosphorylation
S420 Phosphorylation
S421 Phosphorylation
S424 Phosphorylation
T428 Phosphorylation
S431 Phosphorylation
S435 Phosphorylation
S436 Phosphorylation
S437 Phosphorylation
S440 Phosphorylation
S449 Phosphorylation
S454 Phosphorylation
S455 Phosphorylation
S456 Phosphorylation
T458 Phosphorylation
S459 Phosphorylation
S472 Phosphorylation
S474 Phosphorylation
T476 Phosphorylation
S478 Phosphorylation
S484 Phosphorylation
S486 Phosphorylation
T489 Phosphorylation
S495 Phosphorylation
S497 Phosphorylation
T499 Phosphorylation
S506 Phosphorylation
S508 Phosphorylation
S510 Phosphorylation
S525 Phosphorylation
S527 Phosphorylation
S534 Phosphorylation
S536 Phosphorylation
S543 Phosphorylation
S562 Phosphorylation
S564 Phosphorylation
S566 Phosphorylation
T569 Phosphorylation
S573 Phosphorylation
S575 Phosphorylation
T577 Phosphorylation
S584 Phosphorylation
S586 Phosphorylation
T588 Phosphorylation
S594 Phosphorylation
S596 Phosphorylation
T598 Phosphorylation
T600 Phosphorylation
S604 Phosphorylation
S606 Phosphorylation
T608 Phosphorylation
S615 Phosphorylation
S617 Phosphorylation
T619 Phosphorylation
S625 Phosphorylation
T627 Phosphorylation
S629 Phosphorylation
S647 Phosphorylation
S649 Phosphorylation
T651 Phosphorylation
S658 Phosphorylation
S660 Phosphorylation
T662 Phosphorylation
S669 Phosphorylation
S671 Phosphorylation
T673 Phosphorylation
S681 Phosphorylation
S683 Phosphorylation
T685 Phosphorylation
S692 Phosphorylation
S694 Phosphorylation
T696 Phosphorylation
S702 Phosphorylation
S704 Phosphorylation
S706 Phosphorylation
S713 Phosphorylation
S715 Phosphorylation
T717 Phosphorylation
S724 Phosphorylation
S726 Phosphorylation
S727 Phosphorylation
S741 Phosphorylation
S743 Phosphorylation
S745 Phosphorylation
S746 Phosphorylation
S752 Phosphorylation
S755 Phosphorylation
S756 Phosphorylation
S759 Phosphorylation
S761 Phosphorylation
S763 Phosphorylation
S764 Phosphorylation
S767 Phosphorylation
S771 Phosphorylation
S774 Phosphorylation
S778 Phosphorylation
S780 Phosphorylation
S782 Phosphorylation
S783 Phosphorylation
S790 Phosphorylation
T792 Phosphorylation
S797 Phosphorylation
S808 Phosphorylation
T810 Phosphorylation
S815 Phosphorylation
S818 Phosphorylation
S819 Phosphorylation
S820 Phosphorylation
K824 Methylation
K824 Ubiquitination
S827 Phosphorylation
T829 Phosphorylation
S831 Phosphorylation
S837 Phosphorylation
S838 Phosphorylation
S839 Phosphorylation
S846 Phosphorylation
T848 Phosphorylation
S854 Phosphorylation
T856 Phosphorylation
S857 Phosphorylation
S864 Phosphorylation
T866 Phosphorylation P06493 (CDK1)
S871 Phosphorylation
C872 S-Nitrosylation
S875 Phosphorylation
S876 Phosphorylation
S883 Phosphorylation
T885 Phosphorylation
S887 Phosphorylation
S890 Phosphorylation
S892 Phosphorylation
S894 Phosphorylation
S895 Phosphorylation
S901 Phosphorylation
S902 Phosphorylation
T903 Phosphorylation
S908 Phosphorylation
S910 Phosphorylation
S912 Phosphorylation
S913 Phosphorylation
S914 Phosphorylation
S924 Phosphorylation
S929 Phosphorylation
S931 Phosphorylation
S933 Phosphorylation
S934 Phosphorylation
S935 Phosphorylation
S937 Phosphorylation
S939 Phosphorylation
T942 Phosphorylation
R944 Methylation
T945 Phosphorylation
T946 Phosphorylation
R949 Methylation
S950 Phosphorylation
S952 Phosphorylation
S954 Phosphorylation
C956 S-Nitrosylation
S957 Phosphorylation
S961 Phosphorylation
Y967 Phosphorylation
S968 Phosphorylation
S970 Phosphorylation
S972 Phosphorylation
S973 Phosphorylation
S974 Phosphorylation
T977 Phosphorylation
T983 Phosphorylation
S988 Phosphorylation
S990 Phosphorylation
S992 Phosphorylation
S994 Phosphorylation
Y996 Phosphorylation
K998 Ubiquitination
T1003 Phosphorylation
S1008 Phosphorylation
S1010 Phosphorylation
S1012 Phosphorylation
S1014 Phosphorylation
S1021 Phosphorylation
S1024 Phosphorylation
S1028 Phosphorylation
S1032 Phosphorylation
S1034 Phosphorylation
S1041 Phosphorylation
S1042 Phosphorylation
T1043 Phosphorylation
S1048 Phosphorylation
Y1049 Phosphorylation
S1054 Phosphorylation
S1061 Phosphorylation
T1063 Phosphorylation
S1064 Phosphorylation
S1069 Phosphorylation
T1071 Phosphorylation
S1072 Phosphorylation
S1073 Phosphorylation
S1079 Phosphorylation
S1081 Phosphorylation
S1083 Phosphorylation
S1085 Phosphorylation
S1088 Phosphorylation
S1090 Phosphorylation
T1092 Phosphorylation
S1093 Phosphorylation
S1099 Phosphorylation
S1101 Phosphorylation
S1102 Phosphorylation
S1103 Phosphorylation
T1106 Phosphorylation
S1110 Phosphorylation
S1112 Phosphorylation
S1122 Phosphorylation
S1124 Phosphorylation
S1129 Phosphorylation
S1132 Phosphorylation
S1136 Phosphorylation
S1140 Phosphorylation
S1142 Phosphorylation
S1144 Phosphorylation
Y1145 Phosphorylation
S1150 Phosphorylation
S1152 Phosphorylation
S1157 Phosphorylation
T1161 Phosphorylation
S1164 Phosphorylation
T1177 Phosphorylation
S1179 Phosphorylation
K1186 Acetylation
K1186 Ubiquitination
S1188 Phosphorylation
R1195 Methylation
S1198 Phosphorylation
S1199 Phosphorylation
T1205 Phosphorylation
T1208 Phosphorylation
S1214 Phosphorylation
S1218 Phosphorylation
S1219 Phosphorylation
T1222 Phosphorylation
S1227 Phosphorylation
T1231 Phosphorylation
S1232 Phosphorylation
S1233 Phosphorylation
S1245 Phosphorylation
S1254 Phosphorylation
S1257 Phosphorylation
S1258 Phosphorylation
S1270 Phosphorylation
S1271 Phosphorylation
S1287 Phosphorylation
S1311 Phosphorylation
S1318 Phosphorylation P42345 (MTOR)
S1320 Phosphorylation
S1326 Phosphorylation P42345 (MTOR)
S1329 Phosphorylation P42345 (MTOR)
S1336 Phosphorylation
T1341 Phosphorylation
T1345 Phosphorylation
S1348 Phosphorylation
S1349 Phosphorylation
S1368 Phosphorylation
S1375 Phosphorylation
T1376 Phosphorylation
S1378 Phosphorylation
S1379 Phosphorylation
S1382 Phosphorylation
S1383 Phosphorylation
S1384 Phosphorylation
S1387 Phosphorylation
S1397 Phosphorylation
S1398 Phosphorylation
S1401 Phosphorylation
S1403 Phosphorylation
S1404 Phosphorylation
T1413 Phosphorylation P06493 (CDK1)
S1415 Phosphorylation
S1419 Phosphorylation
S1420 Phosphorylation
S1421 Phosphorylation
S1423 Phosphorylation
S1424 Phosphorylation
T1434 Phosphorylation
S1436 Phosphorylation
R1437 Methylation
R1438 Methylation
S1439 Phosphorylation
S1441 Phosphorylation
S1443 Phosphorylation
S1444 Phosphorylation
S1451 Phosphorylation
T1453 Phosphorylation
S1455 Phosphorylation
S1458 Phosphorylation
S1460 Phosphorylation
S1462 Phosphorylation
S1463 Phosphorylation
K1467 Acetylation
T1472 Phosphorylation
S1474 Phosphorylation
S1478 Phosphorylation
C1480 S-Nitrosylation
S1482 Phosphorylation
S1483 Phosphorylation
T1492 Phosphorylation
S1497 Phosphorylation O14757 (CHEK1)
S1499 Phosphorylation O14757 (CHEK1)
S1501 Phosphorylation
S1502 Phosphorylation
T1511 Phosphorylation
S1517 Phosphorylation
S1519 Phosphorylation
S1521 Phosphorylation
S1522 Phosphorylation
T1527 Phosphorylation
T1531 Phosphorylation
S1537 Phosphorylation
S1539 Phosphorylation
S1541 Phosphorylation
S1542 Phosphorylation
S1550 Phosphorylation
S1552 Phosphorylation
S1559 Phosphorylation
S1561 Phosphorylation
S1562 Phosphorylation
T1569 Phosphorylation
T1571 Phosphorylation
S1577 Phosphorylation
S1579 Phosphorylation
S1581 Phosphorylation
S1582 Phosphorylation
S1587 Phosphorylation
K1588 Methylation
S1589 Phosphorylation
S1592 Phosphorylation
S1596 Phosphorylation
S1598 Phosphorylation
S1600 Phosphorylation
S1601 Phosphorylation
S1616 Phosphorylation
S1618 Phosphorylation
S1620 Phosphorylation
S1621 Phosphorylation
S1636 Phosphorylation
S1638 Phosphorylation
S1640 Phosphorylation
S1641 Phosphorylation
S1648 Phosphorylation
S1652 Phosphorylation
S1653 Phosphorylation
S1654 Phosphorylation
T1655 Phosphorylation
S1657 Phosphorylation
S1658 Phosphorylation
S1672 Phosphorylation
S1674 Phosphorylation
S1675 Phosphorylation
T1680 Phosphorylation
S1682 Phosphorylation
T1684 Phosphorylation
S1690 Phosphorylation
S1691 Phosphorylation
S1693 Phosphorylation
S1694 Phosphorylation
T1698 Phosphorylation
S1707 Phosphorylation
S1709 Phosphorylation
S1711 Phosphorylation
S1713 Phosphorylation
T1716 Phosphorylation
S1718 Phosphorylation
T1720 Phosphorylation
S1727 Phosphorylation
S1729 Phosphorylation
S1731 Phosphorylation
S1732 Phosphorylation
S1739 Phosphorylation
S1742 Phosphorylation
S1747 Phosphorylation
S1749 Phosphorylation
S1750 Phosphorylation
S1757 Phosphorylation
S1762 Phosphorylation
S1764 Phosphorylation
S1773 Phosphorylation
T1784 Phosphorylation
S1791 Phosphorylation
S1793 Phosphorylation
S1794 Phosphorylation
S1796 Phosphorylation
S1818 Phosphorylation
Y1820 Phosphorylation
S1822 Phosphorylation
S1824 Phosphorylation
S1830 Phosphorylation
S1831 Phosphorylation
S1834 Phosphorylation
S1842 Phosphorylation
T1844 Phosphorylation
T1847 Phosphorylation
S1848 Phosphorylation
S1852 Phosphorylation
S1854 Phosphorylation
T1856 Phosphorylation
S1857 Phosphorylation
S1864 Phosphorylation
S1866 Phosphorylation
S1869 Phosphorylation
T1872 Phosphorylation
S1876 Phosphorylation
S1878 Phosphorylation
T1880 Phosphorylation
S1884 Phosphorylation
S1888 Phosphorylation
S1890 Phosphorylation
T1892 Phosphorylation
S1893 Phosphorylation
S1896 Phosphorylation
S1900 Phosphorylation
S1902 Phosphorylation
T1904 Phosphorylation
S1905 Phosphorylation
T1907 Phosphorylation
S1911 Phosphorylation
S1913 Phosphorylation
S1916 Phosphorylation
S1919 Phosphorylation
S1923 Phosphorylation
S1925 Phosphorylation
T1927 Phosphorylation
T1931 Phosphorylation
S1935 Phosphorylation
S1937 Phosphorylation
T1939 Phosphorylation
T1941 Phosphorylation
S1946 Phosphorylation
S1948 Phosphorylation
T1950 Phosphorylation
T1954 Phosphorylation
S1958 Phosphorylation
S1960 Phosphorylation
T1962 Phosphorylation
T1966 Phosphorylation
S1970 Phosphorylation
S1972 Phosphorylation
T1974 Phosphorylation
S1975 Phosphorylation
T1978 Phosphorylation
S1982 Phosphorylation
S1984 Phosphorylation
T1986 Phosphorylation
S1987 Phosphorylation
T1990 Phosphorylation
S1994 Phosphorylation
S1996 Phosphorylation
T1998 Phosphorylation
S1999 Phosphorylation
T2002 Phosphorylation
S2006 Phosphorylation
S2008 Phosphorylation
T2010 Phosphorylation
S2011 Phosphorylation
T2014 Phosphorylation
S2018 Phosphorylation
S2020 Phosphorylation
T2022 Phosphorylation
S2030 Phosphorylation
S2032 Phosphorylation
T2034 Phosphorylation
S2042 Phosphorylation
S2044 Phosphorylation
S2046 Phosphorylation
S2054 Phosphorylation
S2056 Phosphorylation
T2058 Phosphorylation
T2061 Phosphorylation
S2067 Phosphorylation
T2069 Phosphorylation
S2071 Phosphorylation
S2079 Phosphorylation
S2081 Phosphorylation
S2083 Phosphorylation
S2088 Phosphorylation
S2090 Phosphorylation
T2092 Phosphorylation
T2096 Phosphorylation
S2100 Phosphorylation
S2102 Phosphorylation
T2104 Phosphorylation
S2111 Phosphorylation
S2112 Phosphorylation
S2115 Phosphorylation
S2118 Phosphorylation
S2121 Phosphorylation
S2123 Phosphorylation
T2125 Phosphorylation
R2129 Methylation
S2132 Phosphorylation
T2144 Phosphorylation
S2147 Phosphorylation
S2155 Phosphorylation
R2163 Methylation
S2171 Phosphorylation
T2186 Phosphorylation
T2192 Phosphorylation
R2194 Methylation
S2200 Phosphorylation
R2207 Methylation
S2209 Phosphorylation
S2219 Phosphorylation
R2221 Methylation
T2222 Phosphorylation
S2230 Phosphorylation
R2231 Methylation
S2236 O-Glycosylation
S2236 Phosphorylation
S2244 Phosphorylation
R2246 Methylation
T2247 Phosphorylation
T2252 Phosphorylation O14757 (CHEK1)
S2259 Phosphorylation
R2260 Methylation
T2261 Phosphorylation
S2272 Phosphorylation
R2274 Methylation
S2280 Phosphorylation O14757 (CHEK1)
R2288 Methylation
T2289 Phosphorylation
T2291 Phosphorylation
R2301 Methylation
T2302 Phosphorylation
S2310 Phosphorylation
T2312 Phosphorylation
S2314 Phosphorylation
T2316 Phosphorylation
T2319 Phosphorylation
Y2323 Phosphorylation
S2325 Phosphorylation
S2326 Phosphorylation
T2329 Phosphorylation
S2335 Phosphorylation
R2342 Methylation
S2343 Phosphorylation
T2347 Phosphorylation
S2355 Phosphorylation
R2356 Methylation
T2357 Phosphorylation
S2365 Phosphorylation
T2367 Phosphorylation
S2368 Phosphorylation
R2370 Methylation
S2376 Phosphorylation
T2381 Phosphorylation
S2382 Phosphorylation
R2384 Methylation
S2388 Phosphorylation O14757 (CHEK1)
Y2390 Phosphorylation
R2392 Methylation
S2394 Phosphorylation
T2397 Phosphorylation
S2398 Phosphorylation
S2407 Phosphorylation
T2409 Phosphorylation
S2412 Phosphorylation
S2415 Phosphorylation
S2417 Phosphorylation
S2421 Phosphorylation
S2426 Phosphorylation
S2428 Phosphorylation
S2429 Phosphorylation
S2436 Phosphorylation
S2438 Phosphorylation
S2449 Phosphorylation
S2453 Phosphorylation
S2456 Phosphorylation
S2459 Phosphorylation
T2467 Phosphorylation
S2532 Phosphorylation
S2534 Phosphorylation
S2535 Phosphorylation
S2536 Phosphorylation
S2537 Phosphorylation
S2538 Phosphorylation
S2539 Phosphorylation
S2540 Phosphorylation
S2542 Phosphorylation
S2543 Phosphorylation
S2544 Phosphorylation
S2545 Phosphorylation
S2546 Phosphorylation
S2550 Phosphorylation
S2551 Phosphorylation
S2552 Phosphorylation
S2563 Phosphorylation
S2581 Phosphorylation
T2583 Phosphorylation
T2599 Phosphorylation
K2602 Acetylation
S2607 Phosphorylation
S2608 Phosphorylation
S2609 Phosphorylation
S2610 Phosphorylation
S2611 Phosphorylation
S2612 Phosphorylation
S2613 Phosphorylation
S2614 Phosphorylation
S2616 Phosphorylation
S2617 Phosphorylation
S2618 Phosphorylation
S2619 Phosphorylation
S2620 Phosphorylation
S2621 Phosphorylation
S2622 Phosphorylation
S2623 Phosphorylation
S2625 Phosphorylation
S2626 Phosphorylation
S2627 Phosphorylation
S2628 Phosphorylation
S2629 Phosphorylation
S2630 Phosphorylation
S2631 Phosphorylation
S2634 Phosphorylation
S2635 Phosphorylation
S2636 Phosphorylation
S2637 Phosphorylation
S2638 Phosphorylation
S2639 Phosphorylation
S2642 Phosphorylation
S2645 Phosphorylation
S2646 Phosphorylation
S2647 Phosphorylation
S2650 Phosphorylation
S2664 Phosphorylation
S2675 Phosphorylation
S2677 Phosphorylation
K2680 Acetylation
K2680 Ubiquitination
S2684 Phosphorylation
S2688 Phosphorylation
S2690 Phosphorylation
S2692 Phosphorylation
Y2693 Phosphorylation
S2694 Phosphorylation
S2702 Phosphorylation
S2706 Phosphorylation
S2714 Phosphorylation
S2727 Phosphorylation
S2729 Phosphorylation
T2738 Phosphorylation
S2740 Phosphorylation
S2749 Phosphorylation
S2751 Phosphorylation

Research Backgrounds

Function:

Required for pre-mRNA splicing as component of the spliceosome.

Subcellular Location:

Nucleus. Nucleus speckle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in liver, placenta, and white blood cells.

Subunit Structure:

Component of pre-catalytic, catalytic and post-catalytic spliceosome complexes. Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRP70, SNRPA1, SRRM1 and SRRM2.

Family&Domains:

Belongs to the CWC21 family.

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