CRLF3 Antibody - #DF8931
| Product: | CRLF3 Antibody |
| Catalog: | DF8931 |
| Description: | Rabbit polyclonal antibody to CRLF3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 50 kDa; 50kD(Calculated). |
| Uniprot: | Q8IUI8 |
| RRID: | AB_2842127 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8931, RRID:AB_2842127.
Fold/Unfold
CREME 9; CREME9; CRLF 3; CRLM9; Cytokine receptor like factor 3; Cytokine receptor like molecule 9; Cytokine receptor related protein 4; CYTOR4; FRWS; MGC20661; P48; p48.2; Type I cytokine receptor like factor; Type I cytokine receptor like factor p48;
Immunogens
Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK).
- Q8IUI8 CRLF3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRGAMELEPELLLQEARENVEAAQSYRRELGHRLEGLREARRQIKESASQTRDVLKQHFNDLKGTLGKLLDERLVTLLQEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGEIAMLGGVGEENEKLWSFTKKASHIQLDSLPEVPLLVDVPCLSAQLDDSILNIVKDHIFKHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDFTAQDYRLQFRKCTSNHFEDVYVGSETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQIGHSTLVPHEWTAGFEGYSLSSRRNIALRNDSESSGVLYSRAPTYFCGQTLTFRVETVGQPDRRDSIGVCAEKQDGYDSLQRDQAVCISTNGAVFVNGKEMTNQLPAVTSGSTVTFDIEAVTLGTTSNNEGGHFKLRVTISSNNREVVFDWLLDQSCGSLYFGCSFFYPGWKVLVF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8IUI8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K45 | Ubiquitination | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| K97 | Acetylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| K339 | Ubiquitination | Uniprot |
Research Backgrounds
May play a role in the negative regulation of cell cycle progression.
Cytoplasm.
Note: The EGFP- and MYC-tagged protein has been shown to be cytoplasmic.
Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK).
Belongs to the cytokine receptor-like factor 3 family.
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