Product: PDCD2 Antibody
Catalog: DF9028
Description: Rabbit polyclonal antibody to PDCD2
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Zebrafish, Bovine, Sheep, Dog, Chicken, Xenopus
Mol.Wt.: 39 kDa; 39kD(Calculated).
Uniprot: Q16342
RRID: AB_2842224

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Zebrafish(100%), Bovine(100%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
PDCD2 Antibody detects endogenous levels of total PDCD2.
RRID:
AB_2842224
Cite Format: Affinity Biosciences Cat# DF9028, RRID:AB_2842224.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

MGC12347; OTTHUMP00000017702; PDCD 2; Pdcd2; PDCD2 protein; PDCD2_HUMAN; Programmed cell death 2; Programmed cell death protein 2; RP 8; RP8; Rp8 homolog; Zinc finger MYND domain containing protein 7; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp 8; Zinc finger protein Rp-8; Zinc finger protein Rp8; ZMYND 7; ZMYND7;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q16342 PDCD2_HUMAN:

Ubiquitous.

Sequence:
MAAAGARPVELGFAESAPAWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSFLLQVYAPLPGRPDAFHRCIFLFCCREQPCCAGLRVFRNQLPRKNDFYSYEPPSENPPPETGESVCLQLKSGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEIVIETEDEIMPEVVEKEDYSEIIGSMGEALEEELDSMAKHESREDKIFQKFKTQIALEPEQILRYGRGIAPIWISGENIPQEKDIPDCPCGAKRILEFQVMPQLLNYLKADRLGKSIDWGILAVFTCAESCSLGTGYTEEFVWKQDVTDTP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Pig
0
Horse
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q16342 As Substrate

Site PTM Type Enzyme
K30 Ubiquitination
K103 Ubiquitination
K129 Ubiquitination
K144 Ubiquitination
K151 Ubiquitination
K157 Sumoylation
K157 Ubiquitination
K239 Sumoylation
K239 Ubiquitination
K243 Ubiquitination
K245 Ubiquitination
K276 Ubiquitination
K286 Ubiquitination
K302 Ubiquitination

Research Backgrounds

Function:

May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.

PTMs:

Ubiquitinated by PRKN, promoting proteasomal degradation.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Restrictive clause

 

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