Product: PDCD2L Antibody
Catalog: DF9030
Description: Rabbit polyclonal antibody to PDCD2L
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Sheep, Dog
Mol.Wt.: 39 kDa; 39kD(Calculated).
Uniprot: Q9BRP1
RRID: AB_2842226

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(80%), Bovine(82%), Sheep(82%), Dog(91%)
Clonality:
Polyclonal
Specificity:
PDCD2L Antibody detects endogenous levels of total PDCD2L.
RRID:
AB_2842226
Cite Format: Affinity Biosciences Cat# DF9030, RRID:AB_2842226.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

MGC144595; PDCD2L; Programmed cell death 2 like; Programmed cell death protein 2 like;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9BRP1 PDD2L_HUMAN:

Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine.

Sequence:
MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVVQVYCPLEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPPGLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGLSVEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
91
Bovine
82
Sheep
82
Pig
80
Rabbit
64
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BRP1 As Substrate

Site PTM Type Enzyme
A2 Acetylation
K6 Ubiquitination
S20 Phosphorylation
T22 Phosphorylation
K31 Ubiquitination
K94 Ubiquitination
S132 Phosphorylation
K240 Ubiquitination
K244 Ubiquitination
S245 Phosphorylation
K252 Ubiquitination

Research Backgrounds

Function:

Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.

Tissue Specificity:

Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.