STRN4 Antibody - #DF9065

(3)  
Product: STRN4 Antibody
Catalog: DF9065
Description: Rabbit polyclonal antibody to STRN4
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Horse, Dog
Mol.Wt.: 80 kDa; 81kD(Calculated).
Uniprot: Q9NRL3
RRID: AB_2842261

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Horse(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
STRN4 Antibody detects endogenous levels of total STRN4.
RRID:
AB_2842261
Cite Format: Affinity Biosciences Cat# DF9065, RRID:AB_2842261.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

PPP2R6C; Protein phosphatase 2 regulatory subunit B'''gamma; Striatin, calmodulin binding protein 4; Striatin-4; STRN4; STRN4_HUMAN; ZIN; Zinedin;

Immunogens

Immunogen:
Uniprot:

Q9NRL3(STRN4_HUMAN) >>Visit HPA database.

Gene(ID):
STRN4(29888)
Sequence:
MMEERAAAAVAAAASSCRPLGSGAGPGPTGAAPVSAPAPGPGPAGKGGGGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKKADVSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGRSLELNGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLGQIPFLQNCEDEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGAPDPRRCTVDGSPHELESRRVKLQGILADLRDVDGLPPKVTGPPPGTPQPRPHEDVFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEPAHIVASFRSGDTVLYDMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAKVFV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NRL3 As Substrate

Site PTM Type Enzyme
S16 Phosphorylation
T29 Phosphorylation
S35 Phosphorylation
S53 Phosphorylation
K111 Ubiquitination
K126 Ubiquitination
K136 Acetylation
K136 Ubiquitination
S161 Phosphorylation
T163 Phosphorylation
S167 Phosphorylation
S201 Phosphorylation
S206 Phosphorylation
S230 Phosphorylation
S234 Phosphorylation
S276 Phosphorylation
S284 Phosphorylation
S312 Phosphorylation
T338 Phosphorylation
S342 Phosphorylation
K352 Ubiquitination
T371 Phosphorylation
T377 Phosphorylation
K431 Ubiquitination
T433 Phosphorylation
S561 Phosphorylation
T718 Phosphorylation
K723 Ubiquitination
S736 Phosphorylation

Research Backgrounds

Function:

Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.

Subcellular Location:

Cytoplasm. Membrane>Peripheral membrane protein. Cell projection>Dendritic spine.
Note: CTTNBP2-binding may regulate dendritic spine distribution.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with CTTNBP2; this interaction may regulate dendritic spine distribution of STRN4. Activation of glutamate receptors weakens the interaction with CTTNBP2 (By similarity). Interacts with CTTNBP2NL.

Family&Domains:

Belongs to the WD repeat striatin family.

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