PSMD9 Antibody - #DF9094
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9094, RRID:AB_2842290.
Fold/Unfold
26S proteasome non ATPase regulatory subunit 9; 26S proteasome non-ATPase regulatory subunit 9; 26S proteasome regulatory subunit p27; Homolog of rat Bridge 1; MGC8644; p27; Proteasome (prosome macropain) 26S subunit non ATPase 9; Proteasome 26S non ATPase regulatory subunit 9; Proteasome 26S subunit non ATPase 9; PSMD 9; Psmd9; PSMD9_HUMAN; Rpn4;
Immunogens
- O00233 PSMD9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAMSRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00233 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| Y41 | Phosphorylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| Y62 | Phosphorylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| Y70 | Phosphorylation | Uniprot | |
| R73 | Methylation | Uniprot | |
| C81 | S-Nitrosylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| S121 | Phosphorylation | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| K211 | Ubiquitination | Uniprot | |
| C216 | S-Nitrosylation | Uniprot |
Research Backgrounds
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process.
Expressed in all tissues tested, highly expressed in liver and kidney.
Interacts with PSMC3. Part of a transient complex (modulator) containing PSMD9, PSMC6 and PSMC3 formed during the assembly of the 26S proteasome.
Belongs to the proteasome subunit p27 family.
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