Factor D/CFD Antibody - #DF9411
| Product: | Factor D/CFD Antibody |
| Catalog: | DF9411 |
| Description: | Rabbit polyclonal antibody to Factor D/CFD |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Sheep, Dog |
| Mol.Wt.: | 27 kDa; 27kD(Calculated). |
| Uniprot: | P00746 |
| RRID: | AB_2842607 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9411, RRID:AB_2842607.
Fold/Unfold
Adipsin; Adipsin/complement factor D; Adn; C3 convertase activator; CFAD_HUMAN; CFD; Complement factor D; complement factor D preproprotein; D component of complement; DF; FactorD; PFD; Properdin factor D;
Immunogens
- P00746 CFAD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00746 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K92 | Ubiquitination | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| R192 | Methylation | Uniprot | |
| K205 | Ubiquitination | Uniprot |
Research Backgrounds
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Secreted.
Belongs to the peptidase S1 family.
Research Fields
· Human Diseases > Infectious diseases: Bacterial > Staphylococcus aureus infection.
· Organismal Systems > Immune system > Complement and coagulation cascades. (View pathway)
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