PABPC3 Antibody - #DF9761

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Product: PABPC3 Antibody
Catalog: DF9761
Description: Rabbit polyclonal antibody to PABPC3
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Monkey
Mol.Wt.: 70 kDa; 70kD(Calculated).
Uniprot: Q9H361
RRID: AB_2842956

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Monkey
Clonality:
Polyclonal
Specificity:
PABPC3 Antibody detects endogenous levels of total PABPC3.
RRID:
AB_2842956
Cite Format: Affinity Biosciences Cat# DF9761, RRID:AB_2842956.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

PABP-3; PABP3; PABP3_HUMAN; PABPC3; PABPL3; Poly(A) binding protein 3; Poly(A)-binding protein 3; Polyadenylate binding protein 3; Polyadenylate-binding protein 3; RP11-165I9.5; Testis specific poly(A) binding protein; Testis-specific poly(A)-binding protein; tPABP;

Immunogens

Immunogen:

A synthesized peptide derived from human PABPC3, corresponding to a region within the internal amino acids.

Uniprot:

Q9H361(PABP3_HUMAN) >>Visit HPA database.

Gene(ID):
PABPC3(5042)
Expression:
Q9H361 PABP3_HUMAN:

Testis specific.

Sequence:
MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV

Research Backgrounds

Function:

Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Testis specific.

Family&Domains:

Belongs to the polyadenylate-binding protein type-1 family.

Research Fields

· Genetic Information Processing > Translation > RNA transport.

· Genetic Information Processing > Translation > mRNA surveillance pathway.

· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.

Restrictive clause

 

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