RABL2B Antibody - #DF9797

(3)  
Product: RABL2B Antibody
Catalog: DF9797
Description: Rabbit polyclonal antibody to RABL2B
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 26 kDa; 26kD(Calculated).
Uniprot: Q9UNT1
RRID: AB_2842991

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RABL2B Antibody detects endogenous levels of total RABL2B.
RRID:
AB_2842991
Cite Format: Affinity Biosciences Cat# DF9797, RRID:AB_2842991.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ78724; FLJ93981; FLJ98216; MGC117180; OTTHUMP00000045491; OTTHUMP00000045492; OTTHUMP00000045493; OTTHUMP00000203788; OTTHUMP00000203792; RAB like 2B; RAB like protein 2B; RAB member of RAS oncogene family like 2B; Rab-like protein 2A; RABL2A; RABL2B; RBL2A_HUMAN; RP11-395L14.2;

Immunogens

Immunogen:

A synthesized peptide derived from human RABL2B, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9UNT1(RBL2B_HUMAN) >>Visit HPA database.

Gene(ID):
RABL2B(11158)
Expression:
Q9UNT1 RBL2B_HUMAN:

Expressed in the testis.

Sequence:
MAEDKTKPSELDQGKYDADDNVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGRTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKVTYRNLSTWYTELREFRPEIPCIVVANKIDDINVTQKSFNFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVSYKQNSQDFMDEIFQELENFSLEQEEEDVPDQEQSSSIETPSEEAASPHS

Research Backgrounds

Function:

Small GTPase required for ciliation. Activated in a guanine nucleotide exchange factor (GEF)-independent manner via its intrinsic GDP for GTP nucleotide exchange ability. Involved in ciliary assembly by binding the intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia.

Subcellular Location:

Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome>Centriole. Cytoplasm>Cytoskeleton>Cilium basal body. Cytoplasm.
Note: Localizes on the mother centriole. Localizes slightly apical to the subdistal appendage, but below the distal appendage.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in the testis.

Family&Domains:

Belongs to the small GTPase superfamily. Rab family.

Restrictive clause

 

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