ARHGEF19 Antibody - #AF9013
(2)
| Product: | ARHGEF19 Antibody |
| Catalog: | AF9013 |
| Description: | Rabbit polyclonal antibody to ARHGEF19 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 90kDa; 89kD(Calculated). |
| Uniprot: | Q8IW93 |
| RRID: | AB_2843204 |
Product Info
Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Prediction:
Bovine(100%), Horse(88%), Sheep(100%), Dog(88%)
Clonality:
Polyclonal
Specificity:
ARHGEF19 Antibody detects endogenous levels of total ARHGEF19.
RRID:
AB_2843204
Cite Format: Affinity Biosciences Cat# AF9013, RRID:AB_2843204.
Cite Format: Affinity Biosciences Cat# AF9013, RRID:AB_2843204.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Arhgef19; ARHGJ_HUMAN; Ephexin-2; Rho guanine nucleotide exchange factor 19; Weakly similar to Rho GEF; WGEF;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- Q8IW93 ARHGJ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDCGPPATLQPHLTGPPGTAHHPVAVCQQESLSFAELPALKPPSPVCLDLFPVAPEELRAPGSRWSLGTPAPLQGLLWPLSPGGSDTEITSGGMRPSRAGSWPHCPGAQPPALEGPWSPRHTQPQRRASHGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQVVQEQALSTEEPRVELSGSTRVSLEGPERRRFSASELMTRLHSSLRLGRNSAARALISGSGTGAAREGKASGMEARSVEMSGDRVSRPAPGDSREGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSAELSECLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPSSPQEDKEVISEGEDCPQVQCVRTYKALHPDELTLEKTDILSVRTWTSDGWLEGVRLADGEKGWVPQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Bovine
100
Sheep
100
Horse
88
Dog
88
Pig
63
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8IW93 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S66 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| S101 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| S336 | Phosphorylation | Uniprot | |
| S338 | Phosphorylation | Uniprot | |
| K423 | Acetylation | Uniprot | |
| K428 | Acetylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| T533 | Phosphorylation | Uniprot | |
| S537 | Phosphorylation | Uniprot | |
| T544 | Phosphorylation | Uniprot | |
| K551 | Methylation | Uniprot | |
| K763 | Ubiquitination | Uniprot | |
| K796 | Ubiquitination | Uniprot |
Research Backgrounds
Function:
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.
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