ARMCX1 Antibody - #AF9014
| Product: | ARMCX1 Antibody |
| Catalog: | AF9014 |
| Description: | Rabbit polyclonal antibody to ARMCX1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Sheep, Dog |
| Mol.Wt.: | 49kDa; 49kD(Calculated). |
| Uniprot: | Q9P291 |
| RRID: | AB_2843205 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF9014, RRID:AB_2843205.
Fold/Unfold
ARMCX 1; AD032; ALEX1; ARM protein lost in epithelial cancers on chromosome X 1; Arm protein lost in epithelial cancers X chromosome 1; Armadillo repeat containing X linked 1; Armadillo repeat containing X linked protein 1; Armadillo repeat-containing X-linked protein 1; ARMCX1; ARMX1_HUMAN; Protein ALEX1;
Immunogens
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.
- Q9P291 ARMX1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRTREAGCVAAGVVIGAGACYCVYRLAWGRDENEKIWDEDEESTDTSEIGVETVKGAKTNAGAGSGAKLQGDSEVKPEVSLGLEDCPGVKEKAHSGSHSGGGLEAKAKALFNTLKEQASAKAGKGARVGTISGNRTLAPSLPCPGGRGGGCHPTRSGSRAGGRASGKSKGKARSKSTRAPATTWPVRRGKFNFPYKIDDILSAPDLQKVLNILERTNDPFIQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTKDPIIREKTYNALNNLSVNAENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRLLTNMTVTNHYQHLLSYSFPDFFALLFLGNHFTKIQIMKLIINFTENPAMTRELVSCKVPSELISLFNKEWDREILLNILTLFENINDNIKNEGLASSRKEFSRSSLFFLFKESGVCVKKIKALANHNDLVVKVKVLKVLTKL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9P291 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S96 | Phosphorylation | Uniprot | |
| S98 | Phosphorylation | Uniprot | |
| S100 | Phosphorylation | Uniprot | |
| R148 | Methylation | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| K254 | Acetylation | Uniprot | |
| K266 | Ubiquitination | Uniprot | |
| T451 | Phosphorylation | Uniprot |
Research Backgrounds
Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.
Mitochondrion. Mitochondrion outer membrane>Single-pass membrane protein.
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.
Interacts with MIRO1.
Belongs to the eutherian X-chromosome-specific Armcx family.
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