Product: BEGAIN Antibody
Catalog: AF9024
Description: Rabbit polyclonal antibody to BEGAIN
Application: WB IHC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Dog
Mol.Wt.: 65kDa; 65kD(Calculated).
Uniprot: Q9BUH8
RRID: AB_2843215

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(90%), Bovine(90%), Horse(100%), Sheep(90%), Dog(100%)
Clonality:
Polyclonal
Specificity:
BEGAIN Antibody detects endogenous levels of total BEGAIN.
RRID:
AB_2843215
Cite Format: Affinity Biosciences Cat# AF9024, RRID:AB_2843215.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Begain; BEGIN; BEGIN_HUMAN; Brain enriched guanylate kinase associated protein; Brain-enriched guanylate kinase-associated homolog (rat); Brain-enriched guanylate kinase-associated protein; KIAA1446; SAP90/PSD95 Associated Proteins; SAPAP;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERRRDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSYSSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPLEAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQGSRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Pig
90
Bovine
90
Sheep
90
Chicken
67
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BUH8 As Substrate

Site PTM Type Enzyme
M1 Acetylation
K11 Ubiquitination
K27 Ubiquitination
K77 Ubiquitination
K112 Ubiquitination
K122 Ubiquitination
K142 Ubiquitination
S167 Phosphorylation
K185 Ubiquitination
K189 Ubiquitination
S200 Phosphorylation
K215 Ubiquitination
S246 Phosphorylation
S346 Phosphorylation
T371 Phosphorylation
S373 Phosphorylation
R381 Methylation
S385 Phosphorylation
S399 Phosphorylation
Y429 Phosphorylation
S440 Phosphorylation
S445 Phosphorylation
S455 Phosphorylation
S465 Phosphorylation
Y468 Phosphorylation
S470 Phosphorylation
S475 Phosphorylation
S477 Phosphorylation
S483 Phosphorylation
S500 Phosphorylation
S502 Phosphorylation
S506 Phosphorylation
S534 Phosphorylation
S553 Phosphorylation
S563 Phosphorylation
Y588 Phosphorylation
T590 Phosphorylation

Research Backgrounds

Function:

May sustain the structure of the postsynaptic density (PSD).

Subcellular Location:

Cytoplasm. Membrane>Peripheral membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with DLG4 and DLGAP1 and forms a ternary complex.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.