Product: CD158f2 Antibody
Catalog: AF9037
Description: Rabbit polyclonal antibody to CD158f2
Application: WB
Reactivity: Human
Mol.Wt.: 40kDa; 41kD(Calculated).
Uniprot: Q8NHK3
RRID: AB_2843228

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Product Info

Source:
Rabbit
Application:
WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
CD158f2 Antibody detects endogenous levels of total CD158f2.
RRID:
AB_2843228
Cite Format: Affinity Biosciences Cat# AF9037, RRID:AB_2843228.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CD_antigen=CD158f2; CD158 antigen-like family member F2; CD158F; CD158f2; Killer cell immunoglobulin-like receptor 2DL5B; Killer cell immunoglobulin-like receptor 2DLX; KIR2DL5; KIR2DL5B; KIR2DLX;

Immunogens

Immunogen:
Uniprot:
Sequence:
MSLMVVSMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTYAQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETTALSQNRVASSHVPAAGI

PTMs - Q8NHK3 As Substrate

Site PTM Type Enzyme
T92 Phosphorylation
Y93 Phosphorylation
S148 Phosphorylation
S149 Phosphorylation
Y153 Phosphorylation
K319 Ubiquitination
K335 Ubiquitination
K344 Ubiquitination

Research Backgrounds

Function:

Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.

Subcellular Location:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the immunoglobulin superfamily.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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