Product: Copine 8 Antibody
Catalog: AF9047
Description: Rabbit polyclonal antibody to Copine 8
Application: WB
Reactivity: Human
Prediction: Pig, Horse, Dog
Mol.Wt.: 65kDa; 63kD(Calculated).
Uniprot: Q86YQ8
RRID: AB_2843238

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(86%), Horse(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
Copine 8 Antibody detects endogenous levels of total Copine 8.
RRID:
AB_2843238
Cite Format: Affinity Biosciences Cat# AF9047, RRID:AB_2843238.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Copine 8; Copine VIII; Copine-8; CPNE8; CPNE8_HUMAN; MGC129645; MGC129646;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Pig
86
Bovine
71
Sheep
71
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q86YQ8 As Substrate

Site PTM Type Enzyme
Y5 Phosphorylation
K58 Ubiquitination
T72 Phosphorylation
K103 Ubiquitination
S104 Phosphorylation
K142 Ubiquitination
K177 Ubiquitination
K198 Ubiquitination
K203 Ubiquitination
S260 Phosphorylation
S356 Phosphorylation
K358 Ubiquitination
K405 Ubiquitination
Y410 Phosphorylation
K545 Ubiquitination
Y553 Phosphorylation
T554 Phosphorylation
T557 Phosphorylation

Research Backgrounds

Function:

Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.

Family&Domains:

Belongs to the copine family.

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