Product: GRIN2 Antibody
Catalog: AF9081
Description: Rabbit polyclonal antibody to GRIN2
Application: WB
Reactivity: Human, Monkey
Prediction: Pig, Horse
Mol.Wt.: 47kDa; 47kD(Calculated).
Uniprot: O60269
RRID: AB_2843272

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Monkey
Prediction:
Pig(88%), Horse(88%)
Clonality:
Polyclonal
Specificity:
GRIN2 Antibody detects endogenous levels of total GRIN2.
RRID:
AB_2843272
Cite Format: Affinity Biosciences Cat# AF9081, RRID:AB_2843272.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C130040D06Rik; C230073P13; G protein-regulated inducer of neurite outgrowth 2; Gm286; GPRIN2; GRIN2; GRIN2_HUMAN; KIAA0514; MGC15171; mKIAA0514; RGD1308922;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O60269 GRIN2_HUMAN:

Expressed specifically in the cerebellum.

Sequence:
MSSSRPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELRKTASSTVWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWWSSTVGNVSTMGGSDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQRAPASEDSLSVEGRRGPLRAVMQSLRRPSCCGCSGAAPE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
88
Horse
88
Bovine
63
Sheep
63
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O60269 As Substrate

Site PTM Type Enzyme
S15 Phosphorylation
S22 Phosphorylation
S24 Phosphorylation
S25 Phosphorylation
S26 Phosphorylation
S27 Phosphorylation
R119 Methylation
S120 Phosphorylation
S122 Phosphorylation
R126 Methylation
S140 Phosphorylation
S142 Phosphorylation
S144 Phosphorylation
S266 Phosphorylation
S424 Phosphorylation
S427 Phosphorylation
S429 Phosphorylation

Research Backgrounds

Function:

May be involved in neurite outgrowth.

Tissue Specificity:

Expressed specifically in the cerebellum.

Subunit Structure:

Interacts with activated forms of GNAO1 and GNAZ.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.