Product: IL-1R9 Antibody
Catalog: AF9096
Description: Rabbit polyclonal antibody to IL-1R9
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 79kDa; 79kD(Calculated).
Uniprot: Q9NP60
RRID: AB_2843287

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
IL-1R9 Antibody detects endogenous levels of total IL-1R9.
RRID:
AB_2843287
Cite Format: Affinity Biosciences Cat# AF9096, RRID:AB_2843287.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

IL 1 RAPL 2; IL 1 receptor accessory protein like 2; IL 1R 9; IL 1R9; IL 1RAPL 2; IL-1 receptor accessory protein-like 2; IL-1-RAPL-2; IL-1R-9; IL-1R9; IL-1RAPL-2; IL1 receptor accessory protein like 2; IL1R9; IL1RAPL 2; IL1RAPL-2; IL1RAPL-2-related protein; IL1RAPL2; IL1RAPL2 related protein; Interleukin 1 receptor 9; Interleukin 1 receptor accessory protein like 2; Interleukin-1 receptor 9; IRPL2_HUMAN; Three immunoglobulin domain containing IL1 receptor related 1; Three immunoglobulin domain-containing IL-1 receptor-related 1; TIGIRR 1; TIGIRR-1; TIGIRR1; X linked interleukin 1 receptor accessory protein like 2; X-linked interleukin-1 receptor accessory protein-like 2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9NP60 IRPL2_HUMAN:

Detected at low levels in fetal and adult brain, in particular in the frontal lobe, temporal lobe and cerebellum. Detected at very low levels in skin, liver, fetal ovary and in placenta.

Sequence:
MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSLGNHHTYCNLPLTLLNGQLPLNNTLKDTQEFHRNSSLLPLSSKELSFTSDIW

PTMs - Q9NP60 As Substrate

Site PTM Type Enzyme
S23 Phosphorylation
S27 Phosphorylation
S35 Phosphorylation
K78 Sumoylation
T122 Phosphorylation
K170 Acetylation
S343 Phosphorylation
Y408 Phosphorylation
T409 Phosphorylation
T455 Phosphorylation
Y456 Phosphorylation
S541 Phosphorylation
S542 Phosphorylation
K543 Acetylation
K547 Acetylation
K560 Acetylation
K561 Acetylation

Research Backgrounds

Subcellular Location:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected at low levels in fetal and adult brain, in particular in the frontal lobe, temporal lobe and cerebellum. Detected at very low levels in skin, liver, fetal ovary and in placenta.

Family&Domains:

The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.

Belongs to the interleukin-1 receptor family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.