KIF13B Antibody - #AF9100

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Product: KIF13B Antibody
Catalog: AF9100
Description: Rabbit polyclonal antibody to KIF13B
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Dog
Mol.Wt.: 202kDa; 203kD(Calculated).
Uniprot: Q9NQT8
RRID: AB_2843291

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Dog(100%)
Clonality:
Polyclonal
Specificity:
KIF13B Antibody detects endogenous levels of total KIF13B.
RRID:
AB_2843291
Cite Format: Affinity Biosciences Cat# AF9100, RRID:AB_2843291.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

GAKIN; Guanylate kinase associated kinesin; KI13B_HUMAN; KIAA0639; KIF 13B; KIF13B; Kinesin 13B; Kinesin family member 13B; Kinesin like protein GAKIN; Kinesin like protein KIF13B; Kinesin-like protein GAKIN; Kinesin-like protein KIF13B; OTTHUMP00000225649;

Immunogens

Immunogen:
Uniprot:

Q9NQT8(KI13B_HUMAN) >>Visit HPA database.

Gene(ID):
KIF13B(23303)
Expression:
Q9NQT8 KI13B_HUMAN:

Ubiquitous.

Sequence:
MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFLESLFYDVKLQYAVPIINQKGEVAGRLHVEVMRLSGDVGERIAGGDEVAEVSFEKETQENKLVCMVKILQATGLPQHLSHFVFCKYSFWDQQEPVIVAPEVDTSSSSVSKEPHCMVVFDHCNEFSVNITEDFIEHLSEGALAIEVYGHKINDPRKNPALWDLGIIQAKTRSLRDRWSEVTRKLEFWVQILEQNENGEYCPVEVISAKDVPTGGIFQLRQGQSRRVQVEVKSVQESGTLPLMEECILSVGIGCVKVRPLRAPRTHETFHEEEEDMDSYQDRDLERLRRKWLNALTKRQEYLDQQLQKLVSKRDKTEDDADREAQLLEMRLTLTEERNAVMVPSAGSGIPGAPAEWTPVPGMETHIPVIFLDLNADDFSSQDNLDDPEAGGWDATLTGEEEEEFFELQIVKQHDGEVKAEASWDSAVHGCPQLSRGTPVDERLFLIVRVTVQLSHPADMQLVLRKRICVNVHGRQGFAQSLLKKMSHRSSIPGCGVTFEIVSNIPEDAQGVEEREALARMAANVENPASADSEAYIEKYLRSVLAVENLLTLDRLRQEVAVKEQLTGKGKLSRRSISSPNVNRLSGSRQDLIPSYSLGSNKGRWESQQDVSQTTVSRGIAPAPALSVSPQNNHSPDPGLSNLAASYLNPVKSFVPQMPKLLKSLFPVRDEKRGKRPSPLAHQPVPRIMVQSASPDIRVTRMEEAQPEMGPDVLVQTMGAPALKICDKPAKVPSPPPVIAVTAVTPAPEAQDGPPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEPEAPISHPPPPTAVPAEEPPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGVELDLPSGKNDGSIGGKQYFRCNPGYGLLVRPSRVRRATGPVRRRSTGLRLGAPEARRSATLSGSATNLASLTAALAKADRSHKNPENRKSWAS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Horse
70
Pig
60
Rabbit
50
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NQT8 As Substrate

Site PTM Type Enzyme
S128 Phosphorylation
T134 Phosphorylation
K195 Ubiquitination
T213 Phosphorylation
S219 Phosphorylation
S220 Phosphorylation
K245 Sumoylation
K271 Ubiquitination
T282 Phosphorylation
S308 Phosphorylation
T311 Phosphorylation
T324 Phosphorylation
S331 Phosphorylation
S342 Phosphorylation
S431 Phosphorylation
S435 Phosphorylation
T506 Phosphorylation Q00535 (CDK5)
S522 Phosphorylation
K622 Acetylation
K622 Ubiquitination
S645 Phosphorylation
S658 Phosphorylation
S661 Phosphorylation
S663 Phosphorylation
Y702 Phosphorylation
S722 Phosphorylation
S723 Phosphorylation
S732 Phosphorylation
Y767 Phosphorylation
S858 Phosphorylation
S1379 Phosphorylation
S1381 Phosphorylation Q7KZI7 (MARK2)
S1382 Phosphorylation
S1389 Phosphorylation
S1391 Phosphorylation
S1400 Phosphorylation
S1410 Phosphorylation Q7KZI7 (MARK2)
S1415 Phosphorylation
S1430 Phosphorylation
S1432 Phosphorylation
S1438 Phosphorylation
Y1450 Phosphorylation
S1481 Phosphorylation
S1497 Phosphorylation
S1537 Phosphorylation
T1545 Phosphorylation
T1548 Phosphorylation
S1559 Phosphorylation
S1562 Phosphorylation
S1644 Phosphorylation
S1654 Phosphorylation
S1658 Phosphorylation
S1689 Phosphorylation
S1691 Phosphorylation
T1771 Phosphorylation
S1778 Phosphorylation
T1779 Phosphorylation
R1782 Methylation
S1791 Phosphorylation
T1793 Phosphorylation
S1795 Phosphorylation
S1797 Phosphorylation
T1799 Phosphorylation
S1803 Phosphorylation
S1814 Phosphorylation
S1823 Phosphorylation
S1826 Phosphorylation

Research Backgrounds

Function:

Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.

PTMs:

Phosphorylated at Ser-1381 and Ser-1410 by MARK2, promoting interaction with 14-3-3 and inhibiting microtubule-dependent accumulation and formation of axons.

Subcellular Location:

Cytoplasm>Cytoskeleton. Cell projection>Axon.
Note: accumulates at the distal part of the microtubules in the tips of axons, but not of dendrites.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Subunit Structure:

Binds to DLG1 and DLG4. Interacts (when phosphorylated at Ser-1381 and Ser-1410) with 14-3-3.

Family&Domains:

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

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