RREB1 Antibody - #AF9187

(1)  
Product: RREB1 Antibody
Catalog: AF9187
Description: Rabbit polyclonal antibody to RREB1
Application: WB
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 180kDa; 181kD(Calculated).
Uniprot: Q92766
RRID: AB_2843377

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(86%)
Clonality:
Polyclonal
Specificity:
RREB1 Antibody detects endogenous levels of total RREB1.
RRID:
AB_2843377
Cite Format: Affinity Biosciences Cat# AF9187, RRID:AB_2843377.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FINB; Finger protein in nuclear bodies; Hindsight homolog; HNT; LZ321; Raf responsive zinc finger protein LZ321; Raf-responsive zinc finger protein LZ321; RAS responsive element binding protein 1; Ras-responsive element-binding protein 1; RREB 1; RREB-1; Rreb1; RREB1_HUMAN; Zep 1; Zep-1; Zep1; Zinc finger motif enhancer binding protein 1; Zinc finger motif enhancer-binding protein 1;

Immunogens

Immunogen:
Uniprot:

Q92766(RREB1_HUMAN) >>Visit HPA database.

Gene(ID):
RREB1(6239)
Expression:
Q92766 RREB1_HUMAN:

Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.

Sequence:
MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASATKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVGME

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
86
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q92766 As Substrate

Site PTM Type Enzyme
T2 Phosphorylation
T31 Phosphorylation
S36 Phosphorylation
S42 Phosphorylation
S44 Phosphorylation
S107 Phosphorylation
S120 Phosphorylation
Y125 Phosphorylation
S161 Phosphorylation
S175 Phosphorylation
S180 Phosphorylation
T229 Phosphorylation
S231 Phosphorylation
K347 Ubiquitination
T351 Phosphorylation
K435 Ubiquitination
K508 Ubiquitination
T514 Phosphorylation
K551 Sumoylation
K566 Ubiquitination
S600 Phosphorylation
K613 Ubiquitination
K615 Sumoylation
K615 Ubiquitination
K624 Ubiquitination
T628 Phosphorylation
K633 Acetylation
K640 Ubiquitination
S694 Phosphorylation
Y706 Phosphorylation
K763 Ubiquitination
K802 Ubiquitination
S848 Phosphorylation
K1085 Ubiquitination
S1103 Phosphorylation
S1107 Phosphorylation
T1120 Phosphorylation
T1121 Phosphorylation
S1122 Phosphorylation
S1134 Phosphorylation
S1135 Phosphorylation
S1140 Phosphorylation
S1161 Phosphorylation
S1167 Phosphorylation
S1174 Phosphorylation
S1175 Phosphorylation
S1180 Phosphorylation
S1194 Phosphorylation
T1204 Phosphorylation
S1219 Phosphorylation
S1225 Phosphorylation
S1238 Phosphorylation
T1267 Phosphorylation
T1269 Phosphorylation
S1271 Phosphorylation
S1273 Phosphorylation
T1277 Phosphorylation
T1315 Phosphorylation
T1318 Phosphorylation
S1320 Phosphorylation
S1388 Phosphorylation
K1400 Acetylation
S1401 Phosphorylation
T1407 Phosphorylation
S1409 Phosphorylation
S1475 Phosphorylation
S1479 Phosphorylation
S1489 Phosphorylation
S1499 Phosphorylation
S1502 Phosphorylation
T1535 Phosphorylation
T1544 Phosphorylation
T1548 Phosphorylation
T1550 Phosphorylation
S1554 Phosphorylation
S1575 Phosphorylation
S1585 Phosphorylation
S1589 Phosphorylation
S1592 Phosphorylation
S1598 Phosphorylation
S1609 Phosphorylation
T1615 Phosphorylation
S1624 Phosphorylation
S1653 Phosphorylation
S1681 Phosphorylation

Research Backgrounds

Function:

Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.

Subcellular Location:

Nucleus speckle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.

Subunit Structure:

Interacts with NEUROD1 and AR.

Family&Domains:

Belongs to the krueppel C2H2-type zinc-finger protein family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.