TAUT Antibody - #AF9208
| Product: | TAUT Antibody |
| Catalog: | AF9208 |
| Description: | Rabbit polyclonal antibody to TAUT |
| Application: | WB IHC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog |
| Mol.Wt.: | 70kDa; 70kD(Calculated). |
| Uniprot: | P31641 |
| RRID: | AB_2843398 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF9208, RRID:AB_2843398.
Fold/Unfold
MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6_HUMAN; SLC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 (neurotransmitter transporter, taurine), member 6; Solute carrier family 6 member 6; TAUT;
Immunogens
Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
- P31641 SC6A6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P31641 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K4 | Ubiquitination | Uniprot | |
| K6 | Ubiquitination | Uniprot | |
| K11 | Sumoylation | Uniprot | |
| K11 | Ubiquitination | Uniprot | |
| K15 | Ubiquitination | Uniprot | |
| K19 | Sumoylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| T28 | Phosphorylation | Uniprot | |
| K37 | Ubiquitination | Uniprot | |
| N190 | N-Glycosylation | Uniprot | |
| K577 | Ubiquitination | Uniprot | |
| K610 | Ubiquitination | Uniprot |
Research Backgrounds
Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
Down-regulated upon Ser-322 phosphorylation.
Cell membrane>Multi-pass membrane protein.
Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
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