TDE1 Antibody - #AF9212
| Product: | TDE1 Antibody |
| Catalog: | AF9212 |
| Description: | Rabbit polyclonal antibody to TDE1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 52kDa; 53kD(Calculated). |
| Uniprot: | Q13530 |
| RRID: | AB_2843402 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF9212, RRID:AB_2843402.
Fold/Unfold
AIGP1; DIFF33; placental transmembrane protein (mouse testicular differentially expressed); SBBI99; serine incorporator 3; TDE; TDE1; TMS 1; Transmembrane protein SBBI99; Tumor differentially expressed 1; Tumor differentially expressed protein 1; Tumour differentially expressed 1;
Immunogens
Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
- Q13530 SERC3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGAVLGVFSLASWVPCLCSGASCLLCSCCPNSKNSTVTRLIYAFILLLSTVVSYIMQRKEMETYLKKIPGFCEGGFKIHEADINADKDCDVLVGYKAVYRISFAMAIFFFVFSLLMFKVKTSKDLRAAVHNGFWFFKIAALIGIMVGSFYIPGGYFSSVWFVVGMIGAALFILIQLVLLVDFAHSWNESWVNRMEEGNPRLWYAALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMSFITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSWVCLLLYVWTLVAPLVLTSRDFS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13530 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K67 | Ubiquitination | Uniprot | |
| K77 | Ubiquitination | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| T310 | Phosphorylation | Uniprot | |
| T355 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| T365 | Phosphorylation | Uniprot | |
| S367 | Phosphorylation | Uniprot | |
| S369 | Phosphorylation | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| S380 | Phosphorylation | Uniprot | |
| S383 | Phosphorylation | Uniprot |
Research Backgrounds
Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm.
N-glycosylated.
Cell membrane>Multi-pass membrane protein. Golgi apparatus membrane>Multi-pass membrane protein.
Cytoplasm>Perinuclear region.
Note: (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable).
Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
Belongs to the TDE1 family.
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