TMC8 Antibody - #AF9215
(2)
| Product: | TMC8 Antibody |
| Catalog: | AF9215 |
| Description: | Rabbit polyclonal antibody to TMC8 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 81kDa; 82kD(Calculated). |
| Uniprot: | Q8IU68 |
| RRID: | AB_2843405 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
TMC8 Antibody detects endogenous levels of total TMC8.
RRID:
AB_2843405
Cite Format: Affinity Biosciences Cat# AF9215, RRID:AB_2843405.
Cite Format: Affinity Biosciences Cat# AF9215, RRID:AB_2843405.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
epidermodysplasia verruciformis 2; Epidermodysplasia verruciformis protein 2; EV2; EVIN2; FLJ40668; FLJ43684; MGC102701; MGC40121; TMC8; Transmembrane channel like protein 8;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Expression:
Sequence:
- Q8IU68 TMC8_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRFPSGAEL
PTMs - Q8IU68 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| S32 | Phosphorylation | Uniprot | |
| T34 | Phosphorylation | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| T321 | Phosphorylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| S522 | Phosphorylation | Uniprot | |
| K630 | Ubiquitination | Uniprot | |
| S656 | Phosphorylation | Uniprot | |
| S658 | Phosphorylation | Uniprot | |
| S666 | Phosphorylation | Uniprot | |
| S669 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot | |
| S683 | Phosphorylation | Uniprot | |
| S703 | Phosphorylation | Uniprot | |
| S722 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Probable ion channel.
Subcellular Location:
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Tissue Specificity:
Expressed in placenta, prostate and testis.
Subunit Structure:
Interacts with CIB1.
Family&Domains:
Belongs to the TMC family.
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