TOM70 Antibody - #DF12045

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Product: TOM70 Antibody
Catalog: DF12045
Description: Rabbit polyclonal antibody to TOM70
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 67 kDa; 67kD(Calculated).
Uniprot: O94826
RRID: AB_2844850

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(92%), Xenopus(83%)
Clonality:
Polyclonal
Specificity:
TOM70 Antibody detects endogenous levels of total TOM70.
RRID:
AB_2844850
Cite Format: Affinity Biosciences Cat# DF12045, RRID:AB_2844850.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ9047; Mitochondrial import receptor subunit TOM70; Mitochondrial precursor proteins import receptor; TOM70; TOM70_HUMAN; Tomm70a; Translocase of outer membrane 70 kDa subunit; Translocase of outer membrane TOM70; Translocase of outer mitochondrial membrane 70 homolog A;

Immunogens

Immunogen:
Uniprot:

O94826(TOM70_HUMAN) >>Visit HPA database.

Gene(ID):
TOMM70(9868)
Sequence:
MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Chicken
92
Xenopus
83
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O94826 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S4 Phosphorylation
S19 Phosphorylation
T33 Phosphorylation
R69 Methylation
R71 Methylation
S75 Phosphorylation
K78 Ubiquitination
T85 Phosphorylation
R89 Methylation
S91 Phosphorylation
S96 Phosphorylation
S110 Phosphorylation
K129 Ubiquitination
K148 Ubiquitination
S153 Phosphorylation
Y156 Phosphorylation
K168 Ubiquitination
K170 Ubiquitination
K178 Acetylation
K178 Ubiquitination
K185 Acetylation
K185 Ubiquitination
K188 Acetylation
K204 Ubiquitination
K233 Ubiquitination
K245 Ubiquitination
S253 Phosphorylation
Y260 Phosphorylation
K275 Ubiquitination
S279 Phosphorylation
K293 Ubiquitination
K302 Ubiquitination
Y310 Phosphorylation
K312 Ubiquitination
K319 Ubiquitination
K326 Ubiquitination
Y327 Phosphorylation
Y339 Phosphorylation
K354 Ubiquitination
K359 Acetylation
K359 Ubiquitination
K372 Ubiquitination
S434 Phosphorylation
K441 Acetylation
K441 Ubiquitination
K463 Ubiquitination
K470 Acetylation
K516 Ubiquitination
K524 Ubiquitination
K536 Ubiquitination
Y601 Phosphorylation
K604 Ubiquitination
T607 Phosphorylation

Research Backgrounds

Function:

Receptor that accelerates the import of all mitochondrial precursor proteins.

Subcellular Location:

Mitochondrion outer membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with CAPN8 (By similarity).

Family&Domains:

Belongs to the Tom70 family.

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