ERAL1 Antibody - #DF12072
Product: | ERAL1 Antibody |
Catalog: | DF12072 |
Description: | Rabbit polyclonal antibody to ERAL1 |
Application: | WB IHC IF/ICC |
Reactivity: | Human, Mouse |
Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
Mol.Wt.: | 50-52 kDa; 48kD(Calculated). |
Uniprot: | O75616 |
RRID: | AB_2844877 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12072, RRID:AB_2844877.
Fold/Unfold
CEGA; Conserved ERA like GTPase; Conserved ERA-like GTPase; ERA; Era (E. coli G protein homolog) like 1; Era G protein like 1 (E. coli); Era G protein like 1; ERA W; ERA-like protein 1; ERA-W; Eral1; ERAL1_HUMAN; ERAL1A; ERAW; GTP binding protein era homolog; GTPase Era; GTPase Era, mitochondrial; GTPase human homolog of E. coli essential cell cycle protein Era; H-ERA; HERA A; hERA; HERA B; HERAA; HERAB; mitochondrial;
Immunogens
- O75616 ERAL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPSWRGARLVQSVLRVWQVGPHVARERVIPFSSLLGFQRRCVSCVAGSAFSGPRLASASRSNGQGSALDHFLGFSQPDSSVTPCVPAVSMNRDEQDVLLVHHPDMPENSRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSRKVHTTRCQALGVITEKETQVILLDTPGIISPGKQKRHHLELSLLEDPWKSMESADLVVVLVDVSDKWTRNQLSPQLLRCLTKYSQIPSVLVMNKVDCLKQKSVLLELTAALTEGVVNGKKLKMRQAFHSHPGTHCPSPAVKDPNTQSVGNPQRIGWPHFKEIFMLSALSQEDVKTLKQYLLTQAQPGPWEYHSAVLTSQTPEEICANIIREKLLEHLPQEVPYNVQQKTAVWEEGPGGELVIQQKLLVPKESYVKLLIGPKGHVISQIAQEAGHDLMDIFLCDVDIRLSVKLLK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75616 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S91 | Phosphorylation | Uniprot | |
K126 | Ubiquitination | Uniprot | |
S173 | Phosphorylation | P24941 (CDK2) | Uniprot |
K176 | Ubiquitination | Uniprot | |
S216 | Phosphorylation | Uniprot | |
K284 | Ubiquitination | Uniprot | |
K355 | Ubiquitination | Uniprot | |
K388 | Ubiquitination | Uniprot | |
K393 | Ubiquitination | Uniprot | |
K398 | Ubiquitination | Uniprot |
Research Backgrounds
Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.
Mitochondrion matrix. Mitochondrion inner membrane>Peripheral membrane protein.
Note: Localizes on the matrix side on the mitochondrial inner membrane.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
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