Quiescin Q6 Antibody - #DF12104
| Product: | Quiescin Q6 Antibody |
| Catalog: | DF12104 |
| Description: | Rabbit polyclonal antibody to Quiescin Q6 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 65-94 kDa; 83kD(Calculated). |
| Uniprot: | O00391 |
| RRID: | AB_2844909 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12104, RRID:AB_2844909.
Fold/Unfold
FLJ34858; hQSOX; Human quiescin (Q6) mRNA, partial cds; Q6; QSCN6; QSOX1; QSOX1_HUMAN; Quiescin Q6; Quiescin Q6 sulfhydryl oxidase 1; Skin sulfhydryl oxidase; Sox; Sulfhydryl oxidase 1; Sulfhydryl oxidase 1 precursor;
Immunogens
Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.
- O00391 QSOX1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRALKGHAGHPAA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00391 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T49 | Phosphorylation | Uniprot | |
| N130 | N-Glycosylation | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| N243 | N-Glycosylation | Uniprot | |
| S255 | Phosphorylation | Uniprot | |
| T276 | O-Glycosylation | Uniprot | |
| T277 | O-Glycosylation | Uniprot | |
| T281 | O-Glycosylation | Uniprot | |
| T282 | O-Glycosylation | Uniprot | |
| T289 | O-Glycosylation | Uniprot | |
| Y300 | Phosphorylation | Uniprot | |
| S306 | Phosphorylation | Uniprot | |
| S426 | Phosphorylation | Uniprot | |
| S493 | O-Glycosylation | Uniprot | |
| S549 | O-Glycosylation | Uniprot | |
| S576 | O-Glycosylation | Uniprot | |
| S576 | Phosphorylation | Uniprot | |
| T577 | O-Glycosylation | Uniprot | |
| T577 | Phosphorylation | Uniprot | |
| S588 | O-Glycosylation | Uniprot | |
| S588 | Phosphorylation | Uniprot | |
| T590 | O-Glycosylation | Uniprot | |
| T592 | O-Glycosylation | Uniprot | |
| T592 | Phosphorylation | Uniprot | |
| T593 | O-Glycosylation | Uniprot | |
| T593 | Phosphorylation | Uniprot | |
| S604 | O-Glycosylation | Uniprot | |
| S643 | O-Glycosylation | Uniprot | |
| T647 | O-Glycosylation | Uniprot | |
| S655 | O-Glycosylation | Uniprot | |
| K676 | Ubiquitination | Uniprot | |
| K739 | Ubiquitination | Uniprot |
Research Backgrounds
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.
N-glycosylated. O-glycosylated on Thr and Ser residues.
Golgi apparatus membrane>Single-pass membrane protein. Secreted.
Note: A small proportion is secreted, probably via a proteolytic cleavage that removes the membrane anchor.
Secreted.
Note: Found in the extracellular medium of quiescent cells but is not found in proliferating cells.
Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.
Monomer.
Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
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