CCP1 Antibody | Affinity Biosciences

Product:	CCP1 Antibody
Catalog:	DF12146
Description:	Rabbit polyclonal antibody to CCP1
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Prediction:	Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.:	138 kDa; 138kD(Calculated).
Uniprot:	Q9UPW5
RRID:	AB_2844951

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Prediction:

Pig(100%), Zebrafish(88%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(88%), Dog(100%), Chicken(100%), Xenopus(100%)

Clonality:

Polyclonal

Specificity:

CCP1 Antibody detects endogenous levels of total CCP1.

RRID:

AB_2844951
Cite Format: Affinity Biosciences Cat# DF12146, RRID:AB_2844951.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

CCP1; 1700020N17Rik; 2310001G17Rik; 2900054O13Rik; 4930445M19Rik; 5730402G09Rik; AGTPBP 1; AGTPBP1; ATP/GTP binding protein 1; ATP/GTP-binding protein 1; BB114605; Carboxypeptidase tubulin; CBPC1_HUMAN; Cytosolic carboxypeptidase 1; DKFZp686M20191; KIAA1035; MGC90651; mKIAA1035; Nervous system nuclear protein induced by axotomy; Nervous system nuclear protein induced by axotomy protein 1 homolog; nmf243; NNA1; OTTHUMP00000021581; OTTHUMP00000063553; pcd; Purkinje cell degeneration; RP11-30C23.1; Soluble carboxypeptidase; Tubulinyl Tyr carboxypeptidase; Tyrosine carboxypeptidase;

Immunogens

Immunogen:

Uniprot:

Q9UPW5(CBPC1_HUMAN) >>Visit HPA database.

Gene(ID):

AGTPBP1(23287)

Sequence:

Q9UPW5 CBPC1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MSKLKVIPEKSLTNNSRIVGLLAQLEKINAEPSESDTARYVTSKILHLAQSQEKTRREMTAKGSTGMEILLSTLENTKDLQTTLNILSILVELVSAGGGRRVSFLVTKGGSQILLQLLMNASKESPPHEDLMVQIHSILAKIGPKDKKFGVKARINGALNITLNLVKQNLQNHRLVLPCLQLLRVYSANSVNSVSLGKNGVVELMFKIIGPFSKKNSSLIKVALDTLAALLKSKTNARRAVDRGYVQVLLTIYVDWHRHDNRHRNMLIRKGILQSLKSVTNIKLGRKAFIDANGMKILYNTSQECLAVRTLDPLVNTSSLIMRKCFPKNRLPLPTIKSSFHFQLPVIPVTGPVAQLYSLPPEVDDVVDESDDNDDIDVEAENETENEDDLDQNFKNDDIETDINKLKPQQEPGRTIEDLKMYEHLFPELVDDFQDYDLISKEPKPFVFEGKVRGPIVVPTAGEETSGNSGNLRKVVMKENISSKGDEGEKKSTFMDLAKEDIKDNDRTLQQQPGDQNRTISSVHGLNNDIVKALDRITLQNIPSQTAPGFTAEMKKDCSLPLTVLTCAKACPHMATCGNVLFEGRTVQLGKLCCTGVETEDDEDTESNSSVEQASVEVPDGPTLHDPDLYIEIVKNTKSVPEYSEVAYPDYFGHIPPPFKEPILERPYGVQRTKIAQDIERLIHQSDIIDRVVYDLDNPNYTIPEEGDILKFNSKFESGNLRKVIQIRKNEYDLILNSDINSNHYHQWFYFEVSGMRPGVAYRFNIINCEKSNSQFNYGMQPLMYSVQEALNARPWWIRMGTDICYYKNHFSRSSVAAGGQKGKSYYTITFTVNFPHKDDVCYFAYHYPYTYSTLQMHLQKLESAHNPQQIYFRKDVLCETLSGNSCPLVTITAMPESNYYEHICHFRNRPYVFLSARVHPGETNASWVMKGTLEYLMSNNPTAQSLRESYIFKIVPMLNPDGVINGNHRCSLSGEDLNRQWQSPSPDLHPTIYHAKGLLQYLAAVKRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTNDNATSCDVVEDTGYRTLPKILSHIAPAFCMSSCSFVVEKSKESTARVVVWREIGVQRSYTMESTLCGCDQGKYKGLQIGTRELEEMGAKFCVGLLRLKRLTSPLEYNLPSSLLDFENDLIESSCKVTSPTTYVLDEDEPRFLEEVDYSAESNDELDIELAENVGDYEPSAQEEVLSDSELSRTYLP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Pig

100

Horse

100

Bovine

100

Sheep

100

Dog

100

Xenopus

100

Chicken

100

Zebrafish

Rabbit

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UPW5 As Substrate

Q9UPW5

Site	PTM Type	Source
K10	Ubiquitination	Uniprot
K44	Ubiquitination	Uniprot
K54	Ubiquitination	Uniprot
T60	Phosphorylation	Uniprot
S64	Phosphorylation	Uniprot
T65	Phosphorylation	Uniprot
S103	Phosphorylation	Uniprot
S213	Phosphorylation	Uniprot
K232	Ubiquitination	Uniprot
K277	Ubiquitination	Uniprot
S278	Phosphorylation	Uniprot
T280	Phosphorylation	Uniprot
K283	Ubiquitination	Uniprot
K532	Ubiquitination	Uniprot
K555	Ubiquitination	Uniprot
K660	Ubiquitination	Uniprot
K674	Ubiquitination	Uniprot
K711	Ubiquitination	Uniprot
K1007	Ubiquitination	Uniprot
R1121	Methylation	Uniprot
T1167	Phosphorylation	Uniprot
S1168	Phosphorylation	Uniprot
Y1206	Phosphorylation	Uniprot

Research Backgrounds

Q9UPW5_CBPC1_HUMAN

Function:

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.

Subcellular Location:

Cytoplasm. Cytoplasm>Cytosol. Nucleus. Mitochondrion.
Note: Localizes in both the cytoplasm and nuclei of interphase and dividing cells.

Subunit Structure:

Interacts with MYLK.

Family&Domains:

Belongs to the peptidase M14 family.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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CCP1 Antibody - #DF12146