ZnT6 Antibody - #DF12184
| Product: | ZnT6 Antibody |
| Catalog: | DF12184 |
| Description: | Rabbit polyclonal antibody to ZnT6 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Zebrafish, Horse, Rabbit, Dog, Chicken |
| Mol.Wt.: | 51 kDa; 51kD(Calculated). |
| Uniprot: | Q6NXT4 |
| RRID: | AB_2844989 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12184, RRID:AB_2844989.
Fold/Unfold
FLJ31101; MST103; MSTP103; SLC30A6; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; Zinc transporter like 3; ZnT-6; ZnT6; ZNT6_HUMAN;
Immunogens
Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.
- Q6NXT4 ZNT6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTIHLFRKPQRSFFGKLLREFRLVAADRRSWKILLFGVINLICTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVTLRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALCFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHVIPMPLLKGTDDLNPVTSTPAKPSSPPPEFSFNTPGKNVNPVILLNTQTRPYGFGLNHGHTPYSSMLNQGLGVPGIGATQGLRTGFTNIPSRYGTNNRIGQPRP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6NXT4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K17 | Ubiquitination | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| T376 | Phosphorylation | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| S382 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| T391 | Phosphorylation | Uniprot | |
| R440 | Methylation | Uniprot | |
| R449 | Methylation | Uniprot | |
| R455 | Methylation | Uniprot |
Research Backgrounds
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.
Golgi apparatus>trans-Golgi network membrane>Multi-pass membrane protein.
Note: Found in vesicles.
Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.
Heterooligomer. Interacts with ZNT5 (By similarity).
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
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