ETFB Antibody - #DF12200
| Product: | ETFB Antibody |
| Catalog: | DF12200 |
| Description: | Rabbit polyclonal antibody to ETFB |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 28 kDa; 28kD(Calculated). |
| Uniprot: | P38117 |
| RRID: | AB_2845005 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12200, RRID:AB_2845005.
Fold/Unfold
Beta ETF; Beta-ETF; Electron transfer flavoprotein beta polypeptide; Electron transfer flavoprotein beta subunit; Electron transfer flavoprotein subunit beta; Electron transferring flavoprotein beta polypeptide; etfB; ETFB_HUMAN; FP585; MADD;
Immunogens
Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
- P38117 ETFB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKLKEIGRI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P38117 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K11 | Acetylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| R26 | Methylation | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| C42 | S-Nitrosylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| R85 | Methylation | Uniprot | |
| K110 | Acetylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K114 | Acetylation | Uniprot | |
| K116 | Acetylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| T172 | Phosphorylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| T182 | Phosphorylation | Uniprot | |
| R186 | Methylation | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| T194 | Phosphorylation | Uniprot | |
| K200 | Acetylation | Uniprot | |
| K200 | Methylation | Uniprot | |
| K202 | Methylation | Uniprot | |
| K203 | Methylation | Uniprot | |
| K210 | Acetylation | Uniprot | |
| K210 | Ubiquitination | Uniprot | |
| K221 | Acetylation | Uniprot | |
| S223 | Phosphorylation | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| K248 | Acetylation | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K250 | Ubiquitination | Uniprot |
Research Backgrounds
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role.
Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from acyl-CoA dehydrogenases.
Mitochondrion matrix.
Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
Heterodimer composed of ETFA and ETFB. Identified in a complex that contains ETFA, ETFB and ETFRF1. Interacts with ACADM.
The recognition loop recognizes a hydrophobic patch at the surface of interacting dehydrogenases and acts as a static anchor at the interface.
Belongs to the ETF beta-subunit/FixA family.
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