MTO1 Antibody - #DF12214
| Product: | MTO1 Antibody |
| Catalog: | DF12214 |
| Description: | Rabbit polyclonal antibody to MTO1 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 70-75 kDa; 80kD(Calculated). |
| Uniprot: | Q9Y2Z2 |
| RRID: | AB_2845019 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12214, RRID:AB_2845019.
Fold/Unfold
mitochondrial MTO1 3; mitochondrial translation optimization 1 homolog; protein MTO1 homolog, mitochondrial precursor;
Immunogens
Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea.
- Q9Y2Z2 MTO1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVDGSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLHLNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEKMITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y2Z2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S60 | Phosphorylation | Uniprot | |
| T62 | Phosphorylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K227 | Ubiquitination | Uniprot | |
| K236 | Ubiquitination | Uniprot | |
| K245 | Methylation | Uniprot | |
| K245 | Ubiquitination | Uniprot | |
| K275 | Ubiquitination | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K306 | Ubiquitination | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| K460 | Ubiquitination | Uniprot | |
| Y471 | Phosphorylation | Uniprot | |
| T480 | Phosphorylation | Uniprot | |
| T481 | Phosphorylation | Uniprot | |
| T484 | Phosphorylation | Uniprot | |
| Y488 | Phosphorylation | Uniprot | |
| K516 | Ubiquitination | Uniprot | |
| K533 | Methylation | Uniprot | |
| K533 | Ubiquitination | Uniprot | |
| K544 | Ubiquitination | Uniprot | |
| K552 | Ubiquitination | Uniprot | |
| K555 | Ubiquitination | Uniprot | |
| T564 | Phosphorylation | Uniprot | |
| S567 | Phosphorylation | Uniprot | |
| K577 | Ubiquitination | Uniprot | |
| Y578 | Phosphorylation | Uniprot | |
| K588 | Ubiquitination | Uniprot | |
| Y613 | Phosphorylation | Uniprot | |
| K625 | Ubiquitination | Uniprot | |
| K637 | Ubiquitination | Uniprot | |
| K656 | Ubiquitination | Uniprot | |
| S660 | Phosphorylation | Uniprot | |
| S669 | Phosphorylation | Uniprot | |
| K701 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
Mitochondrion.
Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea.
Belongs to the MnmG family.
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