SECISBP2 Antibody - #DF12228

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Product: SECISBP2 Antibody
Catalog: DF12228
Description: Rabbit polyclonal antibody to SECISBP2
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 95 kDa; 95kD(Calculated).
Uniprot: Q96T21
RRID: AB_2845033

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(83%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Xenopus(92%)
Clonality:
Polyclonal
Specificity:
SECISBP2 Antibody detects endogenous levels of total SECISBP2.
RRID:
AB_2845033
Cite Format: Affinity Biosciences Cat# DF12228, RRID:AB_2845033.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DKFZp686C09169; OTTHUMP00000064929; OTTHUMP00000064930; OTTHUMP00000064931; OTTHUMP00000064932; RP11 89K14.1; SBP 2; SBP2; SEBP2_HUMAN; SECIS binding protein 2; SECIS-binding protein 2; SECISBP 2; SECISBP2; Selenocysteine insertion sequence binding protein 2; Selenocysteine insertion sequence-binding protein 2;

Immunogens

Immunogen:
Uniprot:

Q96T21(SEBP2_HUMAN) >>Visit HPA database.

Gene(ID):
SECISBP2(79048)
Expression:
Q96T21 SEBP2_HUMAN:

Expressed at high levels in testis.

Sequence:
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
92
Zebrafish
83
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96T21 As Substrate

Site PTM Type Enzyme
K15 Acetylation
R26 Methylation
K126 Ubiquitination
K140 Ubiquitination
K158 Ubiquitination
K173 Ubiquitination
S174 Phosphorylation
R176 Methylation
Y184 Phosphorylation
K238 Ubiquitination
S249 Phosphorylation
K260 Ubiquitination
K267 Ubiquitination
K273 Ubiquitination
S288 Phosphorylation
S296 Phosphorylation
T307 Phosphorylation
K326 Ubiquitination
K335 Ubiquitination
S346 Phosphorylation
K353 Ubiquitination
S367 Phosphorylation
S370 Phosphorylation
K384 Ubiquitination
T424 Phosphorylation
S499 Phosphorylation
K533 Acetylation
K650 Ubiquitination
K662 Ubiquitination
K815 Ubiquitination

Research Backgrounds

Function:

Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.

Subcellular Location:

Nucleus.

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed at high levels in testis.

Subunit Structure:

Interacts with SELB.

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