TMOD4 Antibody - #DF12238
| Product: | TMOD4 Antibody |
| Catalog: | DF12238 |
| Description: | Rabbit polyclonal antibody to TMOD4 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 39kd; 39kD(Calculated). |
| Uniprot: | Q9NZQ9 |
| RRID: | AB_2845043 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12238, RRID:AB_2845043.
Fold/Unfold
Actin capping protein; SK TMOD; Sk-Tmod; Skeletal muscle tropomodulin; SKTMOD; TMOD 4; TMOD4; Tropomodulin 4 (muscle); Tropomodulin-4;
Immunogens
- Q9NZQ9 TMOD4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPAEEQITLEPELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKKR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NZQ9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y4 | Phosphorylation | Uniprot | |
| Y11 | Phosphorylation | Uniprot | |
| T55 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| Y71 | Phosphorylation | Uniprot | |
| S253 | Phosphorylation | Uniprot | |
| K274 | Acetylation | Uniprot |
Research Backgrounds
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
Cytoplasm>Cytoskeleton.
Note: In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574).
Highly expressed in skeletal muscle.
Binds to the N-terminus of tropomyosin and to actin.
Belongs to the tropomodulin family.
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