AEBP2 Antibody - #DF12245
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12245, RRID:AB_2845050.
Fold/Unfold
Adipocyte enhancer binding protein 2; Adipocyte enhancer-binding protein 2; AE (adipocyte enhancer) binding protein 2; AE binding protein 2; AE-binding protein 2; AEBP 2; AEBP2; AEBP2_HUMAN; MGC17922; Zinc finger protein AEBP2;
Immunogens
- Q6ZN18 AEBP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAITDMADLEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNCCWDQCQACFNSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6ZN18 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| S18 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| S149 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| S175 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S210 | Phosphorylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| S241 | Phosphorylation | Uniprot | |
| T242 | Phosphorylation | Uniprot | |
| K303 | Ubiquitination | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| K360 | Ubiquitination | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| K473 | Ubiquitination | Uniprot | |
| K479 | Acetylation | Uniprot | |
| K479 | Ubiquitination | Uniprot | |
| K482 | Ubiquitination | Uniprot |
Research Backgrounds
DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.
Nucleus.
Self-associates. Interacts with EED, EZH2, RBBP4 and SUZ12. Component of the PRC2/EED-EZH1 complex, which includes EED, EZH1, SUZ12, RBBP4 and AEBP2 (By similarity). May also interact with RBBP7.
Belongs to the AEBP2/jing C2H2-type zinc-finger family.
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