DBR1 Antibody - #DF12264
| Product: | DBR1 Antibody |
| Catalog: | DF12264 |
| Description: | Rabbit polyclonal antibody to DBR1 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 62 kDa; 62kD(Calculated). |
| Uniprot: | Q9UK59 |
| RRID: | AB_2845069 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12264, RRID:AB_2845069.
Fold/Unfold
DBR1; DBR1_HUMAN; Debranching enzyme homolog 1 (S. cerevisiae); Lariat debranching enzyme; RNA lariat debranching enzyme;
Immunogens
- Q9UK59 DBR1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTLFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNSSTIRSIYHVRNIEVYKLKQLKQPIDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQHQAKDKGQTARATKFLALDKCLPHRDFLQILEIEHDPSAPDYLEYDIEWLTILRATDDLINVTGRLWNMPENNGLHARWDYSATEEGMKEVLEKLNHDLKVPCNFSVTAACYDPSKPQTQMQLIHRINPQTTEFCAQLGIIDINVRLQKSKEEHHVCGEYEEQDDVESNDSGEDQSEYNTDTSALSSINPDEIMLDEEEDEDSIVSAHSGMNTPSVEPSDQASEFSASFSDVRILPGSMIVSSDDTVDSTIDREGKPGGTVESGNGEDLTKVPLKRLSDEHEPEQRKKIKRRNQAIYAAVDDDDDDAA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UK59 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S69 | Phosphorylation | Uniprot | |
| K128 | Acetylation | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| K250 | Ubiquitination | Uniprot | |
| K256 | Ubiquitination | Uniprot | |
| K330 | Ubiquitination | Uniprot | |
| Y396 | Phosphorylation | Uniprot | |
| S464 | Phosphorylation | Uniprot | |
| S474 | Phosphorylation | Uniprot | |
| S478 | Phosphorylation | Uniprot | |
| S479 | Phosphorylation | Uniprot | |
| S485 | Phosphorylation | Uniprot | |
| K492 | Ubiquitination | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| Y533 | Phosphorylation | Uniprot |
Research Backgrounds
Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.
Nucleus.
Belongs to the lariat debranching enzyme family.
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For Research Use Only.
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