STAU1 Antibody - #DF12325
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| Product: | STAU1 Antibody |
| Catalog: | DF12325 |
| Description: | Rabbit polyclonal antibody to STAU1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 55 kDa; 63kD(Calculated). |
| Uniprot: | O95793 |
| RRID: | AB_2845130 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12325, RRID:AB_2845130.
Fold/Unfold
Double stranded RNA binding protein Staufen homolog 1; Double stranded RNA binding protein Staufen homolog; Double-stranded RNA-binding protein Staufen homolog 1; FLJ25010; MGC124588; PPP1R150; STAU; STAU1; STAU1_HUMAN; staufen; Staufen RNA binding protein (Drosophila); Staufen RNA binding protein homolog 1; Staufen, Drosophila, homolog of, 1; Staufen, RNA binding protein, homolog 1 (Drosophila); staufen-like;
Immunogens
Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
- O95793 STAU1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSASITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95793 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| R98 | Methylation | Uniprot | |
| R108 | Methylation | Uniprot | |
| R115 | Methylation | Uniprot | |
| Y116 | Phosphorylation | Uniprot | |
| Y118 | Phosphorylation | Uniprot | |
| K155 | Acetylation | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| K270 | Acetylation | Uniprot | |
| K274 | Ubiquitination | Uniprot | |
| T277 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| Y281 | Phosphorylation | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| T309 | Phosphorylation | Uniprot | |
| K341 | Acetylation | Uniprot | |
| T362 | O-Glycosylation | Uniprot | |
| K363 | Ubiquitination | Uniprot | |
| K367 | Acetylation | Uniprot | |
| K367 | Ubiquitination | Uniprot | |
| T372 | Phosphorylation | Uniprot | |
| K382 | Ubiquitination | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| K399 | Ubiquitination | Uniprot | |
| K448 | Ubiquitination | Uniprot | |
| T464 | Phosphorylation | Uniprot | |
| T467 | Phosphorylation | Uniprot | |
| Y495 | Phosphorylation | Uniprot | |
| Y506 | Phosphorylation | Uniprot | |
| K507 | Ubiquitination | Uniprot | |
| S554 | Phosphorylation | Uniprot | |
| S572 | Phosphorylation | Uniprot |
Research Backgrounds
Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
(Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process.
Cytoplasm. Rough endoplasmic reticulum.
Note: Localizes exclusively with the rough reticulum endoplasmic (RER).
Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
Binds tubulin. Binds with low affinity single-stranded RNA or DNA homopolymers. Interacts with CASC3 in an RNA-dependent manner (By similarity). Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1.
(Microbial infection) Interacts with HERV-K rec and gag proteins.
(Microbial infection) Interacts with HIV-1 GAG polyprotein.
(Microbial infection) Interacts with influenza virus NS1 protein.
(Microbial infection) Interacts with Ebola virus NP, VP30 and VP35.
One of the DRDB could be involved in RER binding.
The C-terminal contains the tubulin binding domain (TBD).
References
Application: IHC Species: Mice Sample: lung tissues
Application: WB Species: Mice Sample: lung tissues
Application: IHC Species: mouse Sample: lung
Application: WB Species: mouse Sample: lung
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