TIMM44 Antibody - #DF12332
| Product: | TIMM44 Antibody |
| Catalog: | DF12332 |
| Description: | Rabbit polyclonal antibody to TIMM44 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Horse, Dog |
| Mol.Wt.: | 45 kDa; 51kD(Calculated). |
| Uniprot: | O43615 |
| RRID: | AB_2845137 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12332, RRID:AB_2845137.
Fold/Unfold
DKFZp686H05241; MIMT44; Mitochondrial inner membrane translocase; TIM44; Translocase of inner mitochondrial membrane 44; Translocase of inner mitochondrial membrane 44 homolog (yeast);
Immunogens
- O43615 TIM44_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAALRSGWCRCPRRCLGSGIQFLSSHNLPHGSTYQMRRPGGELPLSKSYSSGNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQFHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISASSTEQIL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43615 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S61 | Phosphorylation | Uniprot | |
| T128 | Phosphorylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| S180 | Phosphorylation | Uniprot | |
| S185 | Phosphorylation | Uniprot | |
| K187 | Acetylation | Uniprot | |
| K188 | Acetylation | Uniprot | |
| Y201 | Phosphorylation | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| K246 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| S268 | Phosphorylation | Uniprot | |
| T280 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| Y435 | Phosphorylation | Uniprot |
Research Backgrounds
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side. Mitochondrion matrix.
Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2, TIMM44, TIMM16/PAM16 and TIMM14/DNAJC19 (By similarity). The complex interacts with the TIMM23 component of the TIM23 complex.
Belongs to the Tim44 family.
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