ASBT Antibody - #DF12351
| Product: | ASBT Antibody |
| Catalog: | DF12351 |
| Description: | Rabbit polyclonal antibody to ASBT |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Mol.Wt.: | 38-40 kDa; 38kD(Calculated). |
| Uniprot: | Q12908 |
| RRID: | AB_2845156 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12351, RRID:AB_2845156.
Fold/Unfold
Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal; ileal apical sodium-dependent bile acid transporter; Ileal Na(+)/bile acid cotransporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na(+)-dependent ileal bile acid transporter; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; NTCP2_HUMAN; PBAM; SLC10A2; Sodium/taurocholate cotransporting polypeptide; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 (sodium/bile acid cotransporter family), member 2; Solute carrier family 10 member 2;
Immunogens
A synthesized peptide derived from human ASBT, corresponding to a region within C-terminal amino acids.
- Q12908 NTCP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
PTMs - Q12908 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N10 | N-Glycosylation | Uniprot | |
| K312 | Methylation | Uniprot | |
| K313 | Methylation | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| A339 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
Membrane>Multi-pass membrane protein.
Monomer and homodimer.
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
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