Product: CNPY2/MSAP Antibody
Catalog: DF12367
Description: Rabbit polyclonal antibody to CNPY2/MSAP
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 21 kDa; 21kD(Calculated).
Uniprot: Q9Y2B0
RRID: AB_2845172

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
CNPY2/MSAP Antibody detects endogenous levels of total CNPY2/MSAP.
RRID:
AB_2845172
Cite Format: Affinity Biosciences Cat# DF12367, RRID:AB_2845172.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Canopy 2 homolog (zebrafish); Cnpy2; CNPY2_HUMAN; MIR-interacting saposin-like protein; MSAP; Protein canopy homolog 2; Putative secreted protein ZSIG9; TMEM4; Transmembrane protein 4; UNQ1943/PRO4426; ZSIG9;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9Y2B0 CNPY2_HUMAN:

Expressed in different tissues. Highest levels are detected in adult placenta, liver and pancreas.

Sequence:
MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Zebrafish
73
Xenopus
64
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y2B0 As Substrate

Site PTM Type Enzyme
S23 Phosphorylation
K48 Acetylation
K48 Ubiquitination
K49 Acetylation
T50 Phosphorylation
S55 Phosphorylation
S63 Phosphorylation
Y71 Phosphorylation
Y92 Phosphorylation
Y105 Phosphorylation
S115 Phosphorylation
S116 Phosphorylation
S127 Phosphorylation
S130 Phosphorylation

Research Backgrounds

Function:

Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.

Subcellular Location:

Endoplasmic reticulum.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in different tissues. Highest levels are detected in adult placenta, liver and pancreas.

Subunit Structure:

Interacts with MYLIP/MIR.

Family&Domains:

Belongs to the canopy family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.