KCTD12 Antibody - #DF12414
| Product: | KCTD12 Antibody |
| Catalog: | DF12414 |
| Description: | Rabbit polyclonal antibody to KCTD12 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 36 kDa; 36kD(Calculated). |
| Uniprot: | Q96CX2 |
| RRID: | AB_2845219 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12414, RRID:AB_2845219.
Fold/Unfold
C13orf2; BTB/POZ domain-containing protein KCTD12; KCD12_HUMAN; KCTD12; KIAA1778; PFET1; Pfetin; potassium channel tetramerisation domain containing 12 USA; Predominantly fetal expressed T1 domain;
Immunogens
Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
- Q96CX2 KCD12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLELASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASSTDQSEDKIWTSYTEYVFCRE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96CX2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| Y91 | Phosphorylation | Uniprot | |
| Y119 | Phosphorylation | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| T178 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| S185 | Phosphorylation | Uniprot | |
| S187 | Phosphorylation | Uniprot | |
| T196 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| T211 | Phosphorylation | Uniprot | |
| T219 | Phosphorylation | Uniprot | |
| K229 | Acetylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| K246 | Ubiquitination | Uniprot | |
| T252 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| R257 | Methylation | Uniprot |
Research Backgrounds
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
Cell junction>Synapse>Presynaptic cell membrane. Cell junction>Synapse>Postsynaptic cell membrane.
Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
Interacts as a tetramer with GABRB1 and GABRB2.
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