PHF11 Antibody - #DF12450
| Product: | PHF11 Antibody |
| Catalog: | DF12450 |
| Description: | Rabbit polyclonal antibody to PHF11 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Mol.Wt.: | 34 kDa; 38kD(Calculated). |
| Uniprot: | Q9UIL8 |
| RRID: | AB_2845255 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12450, RRID:AB_2845255.
Fold/Unfold
APY; BCAP; BRCA1 C-terminus-associated protein; IgE responsiveness (atopic); IGEL; IGER; IGHER; NY REN 34 antigen; NY-REN-34; NYREN34; PHD finger protein 11; Phf11; PHF11_HUMAN; Renal carcinoma antigen NY-REN-34; RP11-185C18.3;
Immunogens
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta.
- Q9UIL8 PHF11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY
PTMs - Q9UIL8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S5 | Phosphorylation | Uniprot | |
| S17 | Phosphorylation | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K153 | Ubiquitination | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| S185 | Phosphorylation | Uniprot | |
| T194 | Phosphorylation | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K307 | Ubiquitination | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| S328 | Phosphorylation | Uniprot |
Research Backgrounds
Positive regulator of Th1-type cytokine gene expression.
Nucleus.
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta.
Interacts with BRCA1 and RELA.
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