Product: REEP2 Antibody
Catalog: DF12463
Description: Rabbit polyclonal antibody to REEP2
Application: WB IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 28 kDa; 28kD(Calculated).
Uniprot: Q9BRK0
RRID: AB_2845268

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
REEP2 Antibody detects endogenous levels of total REEP2.
RRID:
AB_2845268
Cite Format: Affinity Biosciences Cat# DF12463, RRID:AB_2845268.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C5orf19; Chromosome 5 open reading frame 19; Receptor accessory protein 2; Receptor expression enhancing protein 2; Receptor expression-enhancing protein 2; REEP 2; REEP2; REEP2_HUMAN; SGC32445; SPG72;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9BRK0 REEP2_HUMAN:

Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas (PubMed:11161817). Expressed in circumvallate papillae (PubMed:16720576).

Sequence:
MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGVLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGSLLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLKTRPKKKTSGGGDSA

PTMs - Q9BRK0 As Substrate

Site PTM Type Enzyme
S97 Phosphorylation
K101 Ubiquitination
T108 Phosphorylation
K113 Ubiquitination
K145 Ubiquitination
S148 Phosphorylation
S150 Phosphorylation
S178 Phosphorylation
S208 Phosphorylation
K242 Acetylation
K243 Acetylation
K244 Acetylation

Research Backgrounds

Function:

Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity).

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas. Expressed in circumvallate papillae.

Subunit Structure:

Interacts with odorant receptor proteins.

Family&Domains:

Belongs to the DP1 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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