REEP6 Antibody - #DF12464
| Product: | REEP6 Antibody |
| Catalog: | DF12464 |
| Description: | Rabbit polyclonal antibody to REEP6 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 22 kDa; 23kD(Calculated). |
| Uniprot: | Q96HR9 |
| RRID: | AB_2845269 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12464, RRID:AB_2845269.
Fold/Unfold
0610011M24Rik; C19orf32; Deleted in polyposis 1 like 1; Dp1l1; FLJ25383; OTTMUSP00000020650; OTTMUSP00000020651; OTTMUSP00000020652; OTTMUSP00000021713; OTTMUSP00000021714; Polyposis locus protein 1 like 1; Polyposis locus protein 1-like 1; Receptor accessory protein 6; Receptor expression enhancing protein 6; Receptor expression-enhancing protein 6; REEP6; REEP6_HUMAN; TB2 protein like 1; TB2L1;
Immunogens
Expressed in circumvallate papillae and testis (PubMed:16720576). Expressed in the retina. Isoform 1 is predominantly present in mature optic cups. Isoform 1 expression is confined to the cell body and inner segment of developing rod photoreceptor cells (PubMed:27889058).
- Q96HR9 REEP6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDGLRQRVEHFLEQRNLVTEVLGALEAKTGVEKRYLAAGAVTLLSLYLLFGYGASLLCNLIGFVYPAYASIKAIESPSKDDDTVWLTYWVVYALFGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLSGRALDAAAGITRNVLQVLARSRAGITPVAVAGPSTPLEADLKPSQTPQPKDK
PTMs - Q96HR9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y68 | Phosphorylation | Uniprot | |
| S159 | Phosphorylation | Uniprot |
Research Backgrounds
Required for correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).
Endoplasmic reticulum membrane>Multi-pass membrane protein. Cytoplasmic vesicle>Clathrin-coated vesicle membrane>Multi-pass membrane protein.
Expressed in circumvallate papillae and testis. Expressed in the retina. Isoform 1 is predominantly present in mature optic cups. Isoform 1 expression is confined to the cell body and inner segment of developing rod photoreceptor cells.
Interacts with STX3 (By similarity). Interacts with clathrin (By similarity).
Belongs to the DP1 family.
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