RIC8B Antibody - #DF12465
| Product: | RIC8B Antibody |
| Catalog: | DF12465 |
| Description: | Rabbit polyclonal antibody to RIC8B |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Zebrafish |
| Mol.Wt.: | 61-66 kDa; 59kD(Calculated). |
| Uniprot: | Q9NVN3 |
| RRID: | AB_2845270 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12465, RRID:AB_2845270.
Fold/Unfold
Brain synembrin; brain synembryn; hSyn; Protein Ric-8B; resistance to inhibitors of cholinesterase 8 homolog B (C. elegans); RIC8, C. elegans, homolog of, B; Ric8b; RIC8B_HUMAN; Synembryn, C. elegans, homolog of, B; Synembryn-B;
Immunogens
- Q9NVN3 RIC8B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPTTCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NVN3 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S37 | Phosphorylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| K107 | Ubiquitination | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| S368 | Phosphorylation | Uniprot | |
| T414 | Phosphorylation | Uniprot | |
| S468 | Phosphorylation | Uniprot | |
| T473 | Phosphorylation | Uniprot | |
| K484 | Ubiquitination | Uniprot |
Research Backgrounds
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction.
Cytoplasm>Cell cortex.
Note: Localizes to the cell cortex.
Interacts with GDP-bound G alpha proteins GNAI1, GNAL, GNAS and GNAQ. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.
Belongs to the synembryn family.
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