SEC6 Antibody - #DF12470
| Product: | SEC6 Antibody |
| Catalog: | DF12470 |
| Description: | Rabbit polyclonal antibody to SEC6 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 86 kDa; 86kD(Calculated). |
| Uniprot: | O60645 |
| RRID: | AB_2845275 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12470, RRID:AB_2845275.
Fold/Unfold
EXOC 3; Exoc3; EXOC3_HUMAN; Exocyst complex component 3; Exocyst complex component Sec 6; Exocyst complex component Sec6; rSec 6; Sec 6; Sec 6 homolog; Sec 6p; Sec6; SEC6 L1; SEC6 like 1; Sec6 protein; SEC6L1; Sec6p;
Immunogens
- O60645 EXOC3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCSGLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPAQASPSYVPLFKDIVVPSLNVAKLLK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O60645 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K28 | Acetylation | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| K48 | Methylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| S121 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| T201 | Phosphorylation | Uniprot | |
| K221 | Acetylation | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| T267 | Phosphorylation | Uniprot | |
| K508 | Ubiquitination | Uniprot | |
| K513 | Ubiquitination | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| K624 | Ubiquitination | Uniprot | |
| K708 | Ubiquitination | Uniprot | |
| S723 | Phosphorylation | Uniprot | |
| Y726 | Phosphorylation | Uniprot |
Research Backgrounds
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Cytoplasm. Cytoplasm>Perinuclear region. Cell projection>Growth cone. Midbody. Golgi apparatus. Cell projection>Neuron projection.
Note: Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269).
Expressed in epididymis (at protein level).
The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with EXOC3L1 (By similarity). Interacts with BIRC6/bruce. Interacts with MYRIP (By similarity).
Belongs to the SEC6 family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.