NUTM1 Antibody - #DF12541
(1)
| Product: | NUTM1 Antibody |
| Catalog: | DF12541 |
| Description: | Rabbit polyclonal antibody to NUTM1 |
| Application: | WB |
| Reactivity: | Human |
| Mol.Wt.: | 120 kDa; 120kD(Calculated). |
| Uniprot: | Q86Y26 |
| RRID: | AB_2845503 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Polyclonal
Specificity:
NUTM1 Antibody detects endogenous levels of total NUTM1.
RRID:
AB_2845503
Cite Format: Affinity Biosciences Cat# DF12541, RRID:AB_2845503.
Cite Format: Affinity Biosciences Cat# DF12541, RRID:AB_2845503.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
C15orf55; Chromosome 15 open reading frame 55; DKFZp434O192; MGC138683; MGC138684; Nuclear protein in testis; NUT; NUT_HUMAN; Protein NUT;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Expression:
Sequence:
- Q86Y26 NUTM1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASDGASALPGPDMSMKPSAAPSPSPALPFLPPTSDPPDHPPREPPPQPIMPSVFSPDNPLMLSAFPSSLLVTGDGGPCLSGAGAGKVIVKVKTEGGSAEPSQTQNFILTQTALNSTAPGTPCGGLEGPAPPFVTASNVKTILPSKAVGVSQEGPPGLPPQPPPPVAQLVPIVPLEKAWPGPHGTTGEGGPVATLSKPSLGDRSKISKDVYENFRQWQRYKALARRHLSQSPDTEALSCFLIPVLRSLARLKPTMTLEEGLPLAVQEWEHTSNFDRMIFYEMAERFMEFEAEEMQIQNTQLMNGSQGLSPATPLKLDPLGPLASEVCQQPVYIPKKAASKTRAPRRRQRKAQRPPAPEAPKEIPPEAVKEYVDIMEWLVGTHLATGESDGKQEEEGQQQEEEGMYPDPGLLSYINELCSQKVFVSKVEAVIHPQFLADLLSPEKQRDPLALIEELEQEEGLTLAQLVQKRLMALEEEEDAEAPPSFSGAQLDSSPSGSVEDEDGDGRLRPSPGLQGAGGAACLGKVSSSGKRAREVHGGQEQALDSPRGMHRDGNTLPSPSSWDLQPELAAPQGTPGPLGVERRGSGKVINQVSLHQDGHLGGAGPPGHCLVADRTSEALPLCWQGGFQPESTPSLDAGLAELAPLQGQGLEKQVLGLQKGQQTGGRGVLPQGKEPLAVPWEGSSGAMWGDDRGTPMAQSYDQNPSPRAAGERDDVCLSPGVWLSSEMDAVGLELPVQIEEVIESFQVEKCVTEYQEGCQGLGSRGNISLGPGETLVPGDTESSVIPCGGTVAAAALEKRNYCSLPGPLRANSPPLRSKENQEQSCETVGHPSDLWAEGCFPLLESGDSTLGSSKETLPPTCQGNLLIMGTEDASSLPEASQEAGSRGNSFSPLLETIEPVNILDVKDDCGLQLRVSEDTCPLNVHSYDPQGEGRVDPDLSKPKNLAPLQESQESYTTGTPKATSSHQGLGSTLPRRGTRNAIVPRETSVSKTHRSADRAKGKEKKKKEAEEEDEELSNFAYLLASKLSLSPREHPLSPHHASGGQGSQRASHLLPAGAKGPSKLPYPVAKSGKRALAGGPAPTEKTPHSGAQLGVPREKPLALGVVRPSQPRKRRCDSFVTGRRKKRRRSQ
PTMs - Q86Y26 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T94 | Phosphorylation | Uniprot | |
| S98 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S231 | Phosphorylation | Uniprot | |
| S247 | Phosphorylation | Uniprot | |
| K336 | Acetylation | Uniprot | |
| K525 | Acetylation | Uniprot | |
| K531 | Acetylation | Uniprot | |
| K799 | Ubiquitination | Uniprot | |
| S813 | Phosphorylation | Uniprot | |
| S818 | Phosphorylation | Uniprot | |
| S1026 | Phosphorylation | Uniprot | |
| S1029 | Phosphorylation | Uniprot | |
| S1031 | Phosphorylation | Uniprot | |
| Q1046 | Methylation | Uniprot |
Research Backgrounds
Function:
Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites.
PTMs:
Methylated at Gln-1046 by N6AMT1.
Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.
Subcellular Location:
Cytoplasm. Nucleus.
Note: Shuttles between nucleus and cytoplasm.
Tissue Specificity:
Specifically expressed in testis.
Family&Domains:
Belongs to the NUT family.
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