Product: OSGI1 Antibody
Catalog: DF12546
Description: Rabbit polyclonal antibody to OSGI1
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 61 kDa; 52kD(Calculated).
Uniprot: Q9UJX0
RRID: AB_2845508

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(92%), Horse(100%), Sheep(90%), Rabbit(83%), Dog(100%)
Clonality:
Polyclonal
Specificity:
OSGI1 Antibody detects endogenous levels of total OSGI1.
RRID:
AB_2845508
Cite Format: Affinity Biosciences Cat# DF12546, RRID:AB_2845508.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1700012B18Rik; BDGI; Bone marrow stromal cell derived growth inhibitor; huOKL38; OKL 38; OKL38; OSGIN 1; OTTHUMP00000174992; OTTHUMP00000174993; Ovary kidney and liver protein 38; Oxidative stress induced growth inhibitor 1; Pregnancy induced growth inhibitor; Pregnancy induced growth inhibitor OKL38;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9UJX0 OSGI1_HUMAN:

Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver (PubMed:11459809, PubMed:14570898, PubMed:15569677). Weakly expressed in spleen, heart, kidney, and pancreas (PubMed:15569677). Highly expressed in tumor cells (at protein level) (PubMed:15569677).

Sequence:
MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEAPGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQDSSPLFQVSGFLTRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKPP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Bovine
92
Sheep
90
Rabbit
83
Chicken
67
Xenopus
58
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UJX0 As Substrate

Site PTM Type Enzyme
S95 Phosphorylation
K139 Ubiquitination
T180 Phosphorylation
K193 Ubiquitination
K196 Ubiquitination
K243 Ubiquitination
K268 Ubiquitination
K414 Ubiquitination
K422 Ubiquitination
S431 Phosphorylation
K453 Ubiquitination

Research Backgrounds

Function:

Regulates the differentiation and proliferation through the regulation of cell death.

Tissue Specificity:

Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver. Weakly expressed in spleen, heart, kidney, and pancreas. Highly expressed in tumor cells (at protein level).

Family&Domains:

Belongs to the OKL38 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.